Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 7/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TPMT | P51580 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
| ▸ | RXRG | P48443 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL632366 | 1.00 | AKR1C3 (0.45) | AKR1C3CA1CA2MMP1MMP2 | |
| SCHEMBL2440527 | 0.85 | CA1 (0.41) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL2440525 | 0.85 | CA1 (0.41) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL5373943 | 0.81 | CA1 (0.41) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL19967035 | 0.80 | AKR1C3 (0.42) | AKR1C3APEX1KDM4ETPMTALDH1A1 | |
| SCHEMBL9283066 | 0.79 | AKR1C3 (0.55) | AKR1C3HPGDAPEX1KDM4ERXRA | |
| SCHEMBL1815099 | 0.79 | AKR1C3 (0.45) | AKR1C3APEX1KDM4EALDH1A1MAPT | |
| SCHEMBL9283069 | 0.79 | AKR1C3 (0.55) | AKR1C3HPGDAPEX1KDM4ERXRA | |
| SCHEMBL19070233 | 0.78 | HPGD (0.42) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL544575 | 0.77 | ERN1 (0.42) | AKR1C3CA1CA2MMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2277496-B1 | Dental material containing surface-modified fillers | IVOCLAR VIVADENT AG (LI) | 2016-03-30 | — | — | EP | claimed |
| EP-1749513-B1 | Photopolymerisable dental material with bisacylphosphine oxides as initiator | IVOCLAR VIVADENT AG (LI) | 2009-03-04 | — | — | EP | claimed |
| EP-1749513-A1 | Photopolymerisable dental material with bisacylphosphine oxides as inhibitors | Ivoclar Vivadent AG (LI) | 2007-02-07 | — | — | EP | claimed |
| EP-1374829-B1 | Dental material on the basis of acryloester phosphonic acid | IVOCLAR VIVADENT AG (LI) | 2005-11-02 | — | — | EP | claimed |
| EP-1374829-A1 | Dental material on the basis of acryloester phosphonic acid | Ivoclar Vivadent AG (LI) | 2004-01-02 | — | — | EP | claimed |
| US-20230322820-A1 | BISACYL DIGERMANIUM COMPOUNDS, THEIR PREPARATION AND THEIR USE AS PHOTOINITIATOR FOR RADICAL POLYMERIZATION | EVONIK OPERATIONS GMBH (DE) | 2023-10-12 | — | — | US | disclosed |
| EP-4257592-A1 | BISACYL DIGERMANIUM COMPOUNDS, THEIR PREPARATION AND THEIR USE AS PHOTOINITIATOR FOR RADICAL POLYMERIZATION | Evonik Operations GmbH (DE) | 2023-10-11 | — | — | EP | disclosed |
| EP-3868767-B1 | LONG-WAVE ABSORBENT PHOTOINITIATORS | IVOCLAR VIVADENT AG (LI) | 2022-01-05 | — | — | EP | disclosed |
| EP-2489344-B1 | Dental material based on an anti-microbial compound | IVOCLAR VIVADENT AG (LI) | 2021-03-24 | — | — | EP | disclosed |
| EP-3293215-B1 | POLYMERIZABLE COMPOSITIONS HAVING ACYL TIN PHOTOINITIATORS | IVOCLAR VIVADENT AG (LI) | 2020-10-21 | — | — | EP | disclosed |
| US-10787468-B2 | Acyl germanium photoinitiators and process for the preparation thereof | IVOCLAR VIVADENT AG (LI) | 2020-09-29 | — | — | US | disclosed |
| CN-108137727-B | Acylgermanium photoinitiator and preparation method thereof | 义获嘉伟瓦登特公司 | 2020-07-24 | — | — | CN | disclosed |
| EP-1413569-B1 | Bicyclic cyclopropane derivatives capable of polymerisation and their use in the preparation of dental materials | IVOCLAR VIVADENT AG (LI) | 2006-12-13 | — | — | EP | disclosed |
| EP-1716836-A1 | Surface-modified fillers | Ivoclar Vivadent AG (LI) | 2006-11-02 | — | — | EP | disclosed |
| EP-1374829-B1 | Dental material on the basis of acryloester phosphonic acid | IVOCLAR VIVADENT AG (LI) | 2005-11-02 | — | — | EP | disclosed |
| WO-2005097043-A1 | HARDENING DENTAL MATERIALS FEATURING ADJUSTABLE TRANSLUCENCE | IVOCLAR VIVADENT AG (DE) | 2005-10-20 | — | — | WO | disclosed |
| EP-1510197-A1 | Dental coating material | Firma Ivoclar Vivadent AG (LI) | 2005-03-02 | — | — | EP | disclosed |
| EP-1413569-A1 | Bicyclic cyclopropane derivatives capable of polymerisation and their use in the preparation of dental materials | Ivoclar Vivadent AG (LI) | 2004-04-28 | — | — | EP | disclosed |
| EP-1374829-A1 | Dental material on the basis of acryloester phosphonic acid | Ivoclar Vivadent AG (LI) | 2004-01-02 | — | — | EP | disclosed |
| EP-1374828-A1 | Dental material on the basis of hydroxyalkyl acrylamides | Ivoclar Vivadent AG (LI) | 2004-01-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10787468-B2 | Acyl germanium photoinitiators and process for the preparation thereof | AGPAT5, AGPAT2, GLRA2 | AKR1C3 402/4885CA1 4756/4885CA2 4378/4885 |
| US-20230322820-A1 | BISACYL DIGERMANIUM COMPOUNDS, THEIR PREPARATION AND THEIR USE AS PHOTOINITIATOR FOR RADICAL POLYMERIZATION | GLRA3, GLRA2, CBR3 | AKR1C3 35/4885CA1 3972/4885CA2 2622/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.