SCHEMBL6324145

SCHEMBL6324145

CC/C(=C\CC/C(C)=C/C(=O)O)CC[C@H]1O[C@@]1(C)CC

nearest known ligand 0.44

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.44
ATM Q13315 1/20 0.44
LSS P48449 7/20 0.37
KDM1A O60341 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6324151 1.00 KDM4E (0.44) KDM4EATMLSSKDM1A
SCHEMBL6514517 0.88 LSS (0.49) KDM4EATMLSSKDM1A
SCHEMBL6407444 0.88 LSS (0.49) KDM4EATMLSSKDM1A
SCHEMBL6514523 0.88 LSS (0.49) KDM4EATMLSSKDM1A
SCHEMBL6407451 0.88 LSS (0.49) KDM4EATMLSSKDM1A
SCHEMBL6407449 0.88 LSS (0.49) KDM4EATMLSSKDM1A
SCHEMBL8767062 0.87 LSS (0.35) KDM4EATMLSS
SCHEMBL29722814 0.87 LSS (0.35) KDM4EATMLSS
SCHEMBL7709823 0.87 LSS (0.35) KDM4EATMLSS
SCHEMBL7709819 0.87 LSS (0.35) KDM4EATMLSS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050158764-A1 Recombinant bHLH-PAS/JHR polypeptide and its use to screen potential insecticides WILSON THOMAS G (US) 2005-07-21 US disclosed
US-6887661-B1 Recombinant bHLH-PAS/JHR polypeptide and its use to screen potential insecticides AMERICAN CYANAMID COMPANY (US) 2005-05-03 US disclosed
US-6326165-B1 NUCLEOTIDE SEQUENCES USED FOR THE DETECTION OF PREFERENTIAL BASIC HELIX LOOP HELIX GENES; FOR DETECTION OF INSECTCIDE TOLERANT GENES COLORADO STATE UNIVERSITY RESEARCH FOUNDATION 2001-12-04 US disclosed