⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butane SCHEMBL27968446 | 0.75 | — | — | |
| SCHEMBL3823311 | 0.74 | — | — | |
| Butane SCHEMBL27294851 | 0.68 | TSHR (0.40) | — | |
| Butane SCHEMBL8837772 | 0.68 | — | — | |
| Butane SCHEMBL1159863 | 0.68 | — | — | |
| Butane SCHEMBL663318 | 0.68 | — | — | |
| Butane SCHEMBL3593 | 0.67 | — | — | |
| Butane SCHEMBL8628663 | 0.67 | TSHR (0.50) | — | |
| Butane SCHEMBL9292387 | 0.67 | TSHR (0.50) | — | |
| Butane SCHEMBL2470336 | 0.67 | TSHR (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240350655-A1 | THIOL-CONJUGATION WITH UNSATURATED PHOSPHORUS(V) COMPOUNDS | FORSCHUNGSVERBUND BERLIN E.V. (DE) | 2024-10-24 | — | — | US | disclosed |
| EP-4326335-A1 | THIOL-CONJUGATION WITH UNSATURATED PHOSPHORUS(V) COMPOUNDS | Forschungsverbund Berlin E.V. (DE) | 2024-02-28 | — | — | EP | disclosed |
| WO-2022223783-A9 | THIOL-CONJUGATION WITH UNSATURATED PHOSPHORUS(V) COMPOUNDS | FORSCHUNGSVERBUND BERLIN E.V. (DE) | 2023-03-02 | — | — | WO | disclosed |
| WO-2022223783-A1 | THIOL-CONJUGATION WITH UNSATURATED PHOSPHORUS(V) COMPOUNDS | FORSCHUNGSVERBUND BERLIN E.V. (DE) | 2022-10-27 | — | — | WO | disclosed |
| US-20050288257-A1 | Novel stable compositions of water and oxygen sensitive compounds and their method of preparation | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2005-12-29 | — | — | US | disclosed |
| EP-1216252-B1 | HYDROFORMYLATION USING MULTIDENTATE PHOSPHITE LIGANDS | DU PONT (US) | 2003-11-12 | — | — | EP | disclosed |
| EP-1216252-A1 | HYDROFORMYLATION USING MULTIDENTATE PHOSPHITE LIGANDS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2002-06-26 | — | — | EP | disclosed |
| US-6399534-B2 | CATALYTIC HYDROFORMYLATION | E. I. DU PONT DE NEMOURS AND COMPANY (DE) | 2002-06-04 | — | — | US | disclosed |
| US-20020013503-A1 | Catalytic hydroformylation | INVISTA NORTH AMERICA S.A.R.L. | 2002-01-31 | — | — | US | disclosed |
| US-6307107-B1 | Hydroformylation of acyclic monoethylenically unsaturated compounds to corresponding terminal aldehydes | E.I. DU PONT DE NEMOURS AND COMPANY | 2001-10-23 | — | — | US | disclosed |
| WO-2001021627-A1 | HYDROFORMYLATION USING MULTIDENTATE PHOSPHITE LIGANDS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2001-03-29 | — | — | WO | disclosed |