Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 10/20 | 0.55 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | NCF1 | P14598 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.35 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6324221 | 1.00 | HRH3 (0.55) | HRH3HRH4NCF1ALDH1A1KDM4E | |
| SCHEMBL5787473 | 0.78 | HRH3 (0.83) | HRH3HRH4NCF1ALDH1A1KDM4E | |
| SCHEMBL5790365 | 0.78 | HRH3 (0.83) | HRH3HRH4NCF1ALDH1A1KDM4E | |
| SCHEMBL5788544 | 0.78 | HRH3 (0.83) | HRH3HRH4NCF1ALDH1A1KDM4E | |
| SCHEMBL5787008 | 0.77 | HRH3 (0.81) | HRH3HRH4ALDH1A1KDM4EMBTD1 | |
| SCHEMBL5790297 | 0.77 | HRH3 (0.81) | HRH3HRH4ALDH1A1KDM4EMBTD1 | |
| SCHEMBL5786990 | 0.77 | HRH3 (0.81) | HRH3HRH4ALDH1A1KDM4EMBTD1 | |
| SCHEMBL5786988 | 0.77 | HRH3 (0.81) | HRH3HRH4ALDH1A1KDM4EMBTD1 | |
| SCHEMBL5790685 | 0.74 | HRH3 (0.61) | HRH3HRH4NCF1ALDH1A1KDM4E | |
| SCHEMBL5790681 | 0.74 | HRH3 (0.61) | HRH3HRH4NCF1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050171181-A1 | 3-Benzyloxymethyl-1-(4-pyrrolidin-1-ylmethyl-phenyl)-cyclobutanol for example; treating allergies and mood disorders; use in combination with a histamine H1 antagonist or a neurotransmitter re-uptake blocker | PFIZER INC | 2005-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050171181-A1 | 3-Benzyloxymethyl-1-(4-pyrrolidin-1-ylmethyl-phenyl)-cyclobutanol for example; treating allergies and mood disorders; use in combination with a histamine H1 antagonist or a neurotransmitter re-uptake blocker | HRH3, HRH4, HRH1 | HRH3 1/4885HRH4 2/4885NCF1 3830/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.