Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JMJD6 | Q6NYC1 | 9/20 | 0.55 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.43 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | KDM6B | O15054 | 1/20 | 0.42 |
| ▸ | KDM5C | P41229 | 1/20 | 0.42 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.42 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4129281 | 0.91 | JMJD6 (0.54) | JMJD6PIK3CAKDM4CKDM4EKDM6B | |
| SCHEMBL4768876 | 0.83 | JMJD6 (0.59) | JMJD6PIK3CALMNATP53MAPT | |
| SCHEMBL28332640 | 0.82 | JMJD6 (0.61) | JMJD6PIK3CAKDM4CLMNATP53 | |
| SCHEMBL4122249 | 0.82 | JMJD6 (0.55) | JMJD6KDM4CMAPTALDH1A1L3MBTL1 | |
| SCHEMBL811785 | 0.82 | JMJD6 (0.76) | JMJD6PIK3CAKDM4CKDM4EKDM6B | |
| SCHEMBL30171421 | 0.82 | JMJD6 (0.76) | JMJD6PIK3CAKDM4CKDM4EKDM6B | |
| SCHEMBL28332645 | 0.80 | JMJD6 (0.59) | JMJD6PIK3CAKDM4CLMNATP53 | |
| SCHEMBL4763680 | 0.80 | JMJD6 (0.67) | JMJD6KDM4CLMNATP53MAPT | |
| SCHEMBL4763737 | 0.80 | JMJD6 (0.61) | JMJD6PIK3CAKDM4CLMNATP53 | |
| SCHEMBL4774129 | 0.80 | HTT (0.57) | JMJD6LMNAMAPTNPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050176764-A1 | Medicine for treating cancer | KOWA CO., LTD (JP) | 2005-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050176764-A1 | Medicine for treating cancer | HDAC4, HDAC3, NR4A3 | JMJD6 920/4885PIK3CA 4050/4885KDM4C 198/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.