Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 5/20 | 0.56 |
| ▸ | HPGD | P15428 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6332336 | 0.96 | GAA (0.53) | GAAHTTTSHRHPGDMAPT | |
| SCHEMBL6323563 | 0.95 | TSHR (0.57) | GAAHTTTSHRHPGDMAPT | |
| SCHEMBL6328207 | 0.94 | GAA (0.53) | GAAHTTTSHRHPGDMAPT | |
| SCHEMBL6323802 | 0.91 | HPGD (0.52) | GAAHTTTSHRHPGDMAPT | |
| SCHEMBL6327228 | 0.91 | TSHR (0.58) | GAAHTTTSHRHPGDMAPT | |
| SCHEMBL6324028 | 0.91 | HPGD (0.59) | GAAHTTTSHRHPGDMAPT | |
| SCHEMBL6328519 | 0.91 | TP53 (0.52) | GAAHTTTSHRHPGDMAPT | |
| SCHEMBL6326426 | 0.91 | KMT2A (0.54) | GAAHTTTSHRHPGDMAPT | |
| SCHEMBL6333150 | 0.90 | TP53 (0.50) | GAAHTTTSHRHPGDMAPT | |
| SCHEMBL6330865 | 0.90 | HPGD (0.49) | GAAHTTTSHRHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6924284-B2 | PARP inhibitors | ICOS CORPORATION (US) | 2005-08-02 | — | — | US | disclosed |