Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | ACE | P12821 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3305726 | 0.81 | ATM (0.41) | TSHRCYP3A4MAPTATM | |
| SCHEMBL3303354 | 0.81 | ATM (0.41) | TSHRCYP3A4MAPTATM | |
| SCHEMBL6326567 | 0.80 | NR1H2 (0.40) | TSHRCYP3A4MAPTATM | |
| SCHEMBL6484163 | 0.80 | TSHR (0.38) | TSHRATM | |
| SCHEMBL7164726 | 0.79 | TSHR (0.35) | TSHRCYP3A4ATM | |
| SCHEMBL7164243 | 0.79 | PLG (0.35) | TSHRCYP3A4ATM | |
| SCHEMBL7162429 | 0.79 | TSHR (0.35) | TSHRCYP3A4ATM | |
| SCHEMBL6327750 | 0.79 | TSHR (0.35) | TSHRCYP3A4ATM | |
| SCHEMBL6959922 | 0.79 | TSHR (0.42) | TSHRATMACE | |
| SCHEMBL7167960 | 0.77 | TSHR (0.36) | TSHRCYP3A4MAPTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6953805-B2 | Excitatory amino acid receptor antagonists | ELI LILLY AND COMPANY (US) | 2005-10-11 | — | — | US | disclosed |