Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.68 |
| ▸ | RAB9A | P51151 | 3/20 | 0.68 |
| ▸ | TP53 | P04637 | 3/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.68 |
| ▸ | MAPT | P10636 | 2/20 | 0.68 |
| ▸ | HTT | P42858 | 1/20 | 0.68 |
| ▸ | GFER | P55789 | 1/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.66 |
| ▸ | HPGD | P15428 | 1/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.55 |
| ▸ | BCHE | P06276 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5182011 | 0.92 | NPC1 (0.76) | NPC1RAB9ATP53SMN1; SMN2MAPT | |
| 2-Phenethylbenzo[D]Oxazole SCHEMBL10582102 | 0.84 | MAPT (0.81) | NPC1RAB9ATP53SMN1; SMN2MAPT | |
| SCHEMBL11368928 | 0.83 | NPC1 (0.68) | NPC1RAB9ATP53SMN1; SMN2KDM4E | |
| Hydrochloric Acid SCHEMBL8983501 | 0.83 | NPC1 (0.77) | NPC1RAB9ATP53SMN1; SMN2MAPT | |
| SCHEMBL28868163 | 0.83 | NPC1 (0.68) | NPC1RAB9ATP53SMN1; SMN2KDM4E | |
| SCHEMBL155002 | 0.82 | MAPT (1.00) | NPC1RAB9ATP53SMN1; SMN2MAPT | |
| SCHEMBL31170 | 0.82 | NPC1 (0.81) | NPC1RAB9ATP53SMN1; SMN2MAPT | |
| SCHEMBL8983405 | 0.81 | NPC1 (0.64) | NPC1RAB9ATP53SMN1; SMN2MAPT | |
| SCHEMBL28266940 | 0.81 | NPC1 (0.64) | NPC1RAB9ATP53SMN1; SMN2KDM4E | |
| Methane SCHEMBL29265168 | 0.80 | NPC1 (0.79) | NPC1RAB9ATP53SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050101703-A1 | Method for the production of optically brightened polyester | MARTINI THOMAS (DE) | 2005-05-12 | — | — | US | disclosed |