Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 11/20 | 1.00 |
| ▸ | HTR1A | P08908 | 1/20 | 0.67 |
| ▸ | DRD4 | P21917 | 1/20 | 0.67 |
| ▸ | HTR2A | P28223 | 1/20 | 0.67 |
| ▸ | HTR2C | P28335 | 1/20 | 0.67 |
| ▸ | HTR7 | P34969 | 1/20 | 0.67 |
| ▸ | DRD3 | P35462 | 1/20 | 0.67 |
| ▸ | MAOB | P27338 | 2/20 | 0.62 |
| ▸ | MAOA | P21397 | 1/20 | 0.62 |
| ▸ | HRH1 | P35367 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14287615 | 0.93 | HRH3 (0.88) | HRH3HTR1ADRD4HTR2AHTR2C | |
| SCHEMBL14287616 | 0.86 | HRH3 (0.87) | HRH3MAOBMAOA | |
| SCHEMBL1795697 | 0.85 | HRH3 (0.73) | HRH3HRH1 | |
| SCHEMBL1795300 | 0.85 | HRH3 (0.73) | HRH3DRD3HRH1 | |
| SCHEMBL5100387 | 0.84 | HRH3 (0.72) | HRH3MAOBMAOAHRH1 | |
| Hydrochloric Acid SCHEMBL11564113 | 0.83 | HRH3 (0.71) | HRH3HRH1 | |
| SCHEMBL1795522 | 0.83 | HRH3 (0.71) | HRH3MAOBMAOAHRH1 | |
| SCHEMBL1794444 | 0.83 | HRH3 (0.71) | HRH3HRH1 | |
| SCHEMBL1793430 | 0.83 | HRH3 (0.71) | HRH3DRD3 | |
| SCHEMBL1796426 | 0.83 | HRH3 (0.71) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050209274-A1 | Antagonists of melanin concentrating hormone effects on the melanin concentrating hormone receptor | ABOTT LABORATORIES | 2005-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050209274-A1 | Antagonists of melanin concentrating hormone effects on the melanin concentrating hormone receptor | MCHR1, MCHR2, MC1R | HRH3 199/4885HTR1A 67/4885DRD4 397/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.