Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 7/20 | 0.53 |
| ▸ | PLG | P00747 | 1/20 | 0.34 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 2/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6330812 | 1.00 | HTR2C (0.53) | HTR2CPLGP2RY14NOTUMHTR2B | |
| SCHEMBL6331276 | 1.00 | HTR2C (0.53) | HTR2CPLGP2RY14NOTUMHTR2B | |
| SCHEMBL6331278 | 1.00 | HTR2C (0.53) | HTR2CPLGP2RY14NOTUMHTR2B | |
| SCHEMBL6330817 | 1.00 | HTR2C (0.53) | HTR2CPLGP2RY14NOTUMHTR2B | |
| Hydrochloric Acid SCHEMBL6333598 | 0.99 | HTR2C (0.52) | HTR2CPLGP2RY14NOTUMHTR2B | |
| Hydrochloric Acid SCHEMBL6333603 | 0.99 | HTR2C (0.52) | HTR2CPLGP2RY14NOTUMHTR2B | |
| Hydrochloric Acid SCHEMBL6333599 | 0.99 | HTR2C (0.52) | HTR2CPLGP2RY14NOTUMHTR2B | |
| SCHEMBL3218850 | 0.73 | HTR2C (0.42) | HTR2CPLGP2RY14NOTUMCHRNB2 | |
| Hydrochloric Acid SCHEMBL6332881 | 0.73 | HTR2C (0.46) | HTR2CP2RY14NOTUMHTR2B | |
| Hydrochloric Acid SCHEMBL6332887 | 0.73 | HTR2C (0.46) | HTR2CP2RY14NOTUMHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6881733-B1 | Serotonergic benzofurans | ELI LILLY AND COMPANY (US) | 2005-04-19 | — | — | US | disclosed |
| EP-1204659-B1 | SEROTONERGIC BENZOFURANS | LILLY CO ELI (US) | 2003-11-26 | — | — | EP | disclosed |
| EP-1204659-A2 | SEROTONERGIC BENZOFURANS | ELI LILLY AND COMPANY (US) | 2002-05-15 | — | — | EP | disclosed |
| WO-2001009122-A2 | SEROTONERGIC BENZOFURANS | ELI LILLY AND COMPANY (US) | 2001-02-08 | — | — | WO | disclosed |