Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15842687 | 0.81 | CA12 (0.60) | CYP2A6KDM4ECYP1A2ALDH1A1MAOB | |
| SCHEMBL6337378 | 0.81 | CYP2A6 (0.55) | CYP2A6KDM4ECYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL11094483 | 0.79 | HSD17B3 (0.63) | CYP2A6KDM4ECYP1A2ALDH1A1MAOB | |
| SCHEMBL15842782 | 0.77 | CYP2A6 (0.67) | CYP2A6KDM4EALDH1A1MAOBHPGD | |
| SCHEMBL11180486 | 0.77 | CA9 (0.64) | KDM4ECYP1A2ALDH1A1MAOBMEN1 | |
| SCHEMBL11097757 | 0.76 | MAOB (0.55) | KDM4EALDH1A1MAOBMEN1KMT2A | |
| SCHEMBL7762789 | 0.75 | CYP2A6 (0.63) | CYP2A6KDM4ECYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL15842498 | 0.72 | KDM4E (0.61) | KDM4ECYP1A2ALDH1A1MAOBMEN1 | |
| SCHEMBL15842493 | 0.72 | KDM4E (0.73) | CYP2A6KDM4ECYP1A2ALDH1A1KMT2A | |
| SCHEMBL9009049 | 0.70 | CA9 (0.62) | KDM4ECYP1A2ALDH1A1MAOBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050209274-A1 | Antagonists of melanin concentrating hormone effects on the melanin concentrating hormone receptor | ABOTT LABORATORIES | 2005-09-22 | — | — | US | disclosed |
| EP-0050396-B1 | COUMARIN INTERMEDIATES | BEECHAM GROUP PLC (GB) | 1984-12-27 | — | — | EP | disclosed |
| EP-0050097-B1 | ALPHA-(PYRIDYL-2-OXY-PHENOXY)-PROPIONIC-ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES AND/OR PLANT GROWTH REGULATORS | CIBA-GEIGY AG (CH) | 1984-12-05 | — | — | EP | disclosed |
| EP-0010392-B1 | HETEROCYCLIC COUMARIN DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING SAID DERIVATIVES | BEECHAM GROUP PLC (GB) | 1982-12-29 | — | — | EP | disclosed |
| EP-0050396-A1 | Coumarin intermediates | BEECHAM GROUP PLC (GB) | 1982-04-28 | — | — | EP | disclosed |
| EP-0050097-A1 | Alpha-(pyridyl-2-oxy-phenoxy)-propionic-acid derivatives, process for their preparation and their use as herbicides and/or plant growth regulators | CIBA-GEIGY AG (CH) | 1982-04-21 | — | — | EP | disclosed |
| US-4263299-A | ANTIHISTAMINES, ANTIALLERGENS | BEECHAM GROUP LIMITED (GB) | 1981-04-21 | — | — | US | disclosed |
| EP-0010392-A1 | Heterocyclic coumarin derivatives, their preparation and pharmaceutical compositions comprising said derivatives | BEECHAM GROUP PLC (GB) | 1980-04-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050209274-A1 | Antagonists of melanin concentrating hormone effects on the melanin concentrating hormone receptor | MCHR1, MCHR2, MC1R | CYP2A6 2701/4885KDM4E 2305/4885CYP1A2 1476/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.