⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3583815 | 0.86 | — | — | |
| SCHEMBL9996556 | 0.84 | TAAR1 (0.59) | — | |
| SCHEMBL2030841 | 0.84 | TAAR1 (0.71) | — | |
| SCHEMBL4846134 | 0.82 | TAAR1 (0.57) | — | |
| SCHEMBL150607 | 0.80 | — | — | |
| SCHEMBL1309332 | 0.79 | — | — | |
| SCHEMBL20146704 | 0.79 | TAAR1 (0.73) | — | |
| SCHEMBL20135772 | 0.79 | TAAR1 (0.73) | — | |
| SCHEMBL8571535 | 0.77 | TAAR1 (0.70) | — | |
| SCHEMBL6734915 | 0.77 | TAAR1 (0.70) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104130238-A | Preparation method of rotigotine | INST CHEMISTRY CO LTD HENAN ACADEMY OF SCIENCES | 2014-11-05 | — | — | CN | claimed |
| CN-101787032-A | Novel method for preparing clopidogrel and slat thereof | WUXI HOWFOND PHARMACEUTICAL CO | 2010-07-28 | — | — | CN | claimed |
| EP-4711368-A1 | AZEPINE COMPOUND, AND COMPOSITION AND USE THEREOF | CHENGDU MFS PHARMA. CO., LTD. (CN) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024251275-A1 | AZEPINE COMPOUND, AND COMPOSITION AND USE THEREOF | 成都麻沸散医药科技有限公司 | 2024-12-12 | — | — | WO | disclosed |
| CN-119101054-A | Azepine compound, and composition and application thereof | 成都麻沸散医药科技有限公司 | 2024-12-10 | — | — | CN | disclosed |
| CN-114716296-B | Efficient halogenation synthesis method of alkyl halide | 润药仁智(北京)科技有限公司 | 2023-12-12 | — | — | CN | disclosed |
| CN-113880737-B | Application of novel persulfate reagent in synthesis of asymmetric polysulfide | 安徽农业大学 | 2023-09-15 | — | — | CN | disclosed |
| CN-114716296-A | Efficient halogenation synthesis method of alkyl halide | 北京大学 | 2022-07-08 | — | — | CN | disclosed |
| US-11225480-B2 | Malic enzyme inhibitors | SUN PHARMA ADVANCED RESEARCH COMPANY LTD (IN) | 2022-01-18 | — | — | US | disclosed |
| CN-113880737-A | Application of novel persulfur reagent in synthesis of asymmetric persulfur | 安徽农业大学 | 2022-01-04 | — | — | CN | disclosed |
| US-20210115038-A1 | MALIC ENZYME INHIBITORS | SUN PHARMA ADVANCED RESEARCH COMPANY LTD (IN) | 2021-04-22 | — | — | US | disclosed |
| US-6723745-B2 | PREVENTION OR TREATMENT OF AUTOIMMUNE DISEASE IN WARM BLOODED ANIMAL | SANKYO COMPANY, LIMITED (JP) | 2004-04-20 | — | — | US | disclosed |
| US-20030236297-A1 | Amino alcohol derivatives | SANKYO COMPANY, LIMITED (JP) | 2003-12-25 | — | — | US | disclosed |
| EP-1300405-A1 | AMINO ALCOHOL DERIVATIVES | Sankyo Company, Limited (JP) | 2003-04-09 | — | — | EP | disclosed |
| WO-2003004603-A2 | METHODS OF MODULATING PHARMACOKINETICS OF OLIGONUCLEOTIDES | ISIS PHARMACEUTICALS, INC. (US) | 2003-01-16 | — | — | WO | disclosed |
| EP-0771196-B1 | EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 1999-12-08 | — | — | EP | disclosed |
| US-5717109-A | CARBOXYCYCLOPROPYL GLYCINE DERIVATIVES; USEFUL FOR TREATMENT OF ACUTE OR CHRONIC NEURODEGENERATIVE CONDITIONS, AND AS ANTIPSYCHOTIC, ANTICONVULSANT, ANALGESIC, ANXIOLYTIC, ANTIDEPRESSANT AND ANTI-EMETIC AGENTS | ELI LILLY AND COMPANY (US) | 1998-02-10 | — | — | US | disclosed |
| EP-0771196-A4 | EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 1997-09-03 | — | — | EP | disclosed |
| EP-0771196-A1 | EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1997-05-07 | — | — | EP | disclosed |
| WO-1996007405-A1 | EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1996-03-14 | — | — | WO | disclosed |