Sugi Predict

Sugi Predict / Compounds / Fluoride

Fluoride

Fluoride

SCHEMBL633879

F.c1ccc(CN(Cc2ccccc2)Cc2ccccc2)cc1

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CNR2 P34972 1/20 0.58
▸ TSHR P16473 4/20 0.57
▸ ALDH1A1 P00352 3/20 0.57
▸ AOC3 Q16853 1/20 0.52
▸ TRPA1 O75762 1/20 0.50
▸ CALM1 P0DP23 1/20 0.47
▸ KDM4E B2RXH2 1/20 0.47
▸ CA2 P00918 1/20 0.46
▸ TDP1 Q9NUW8 1/20 0.46
▸ OPRM1 P35372 2/20 0.45
▸ OPRD1 P41143 2/20 0.45
▸ OPRK1 P41145 2/20 0.45
▸ MAPK1 P28482 1/20 0.45
▸ CARM1 Q86X55 1/20 0.44
▸ PRMT6 Q96LA8 1/20 0.44
▸ PRMT8 Q9NR22 1/20 0.44
▸ CYP2C19 P33261 1/20 0.44
▸ MGLL Q99685 1/20 0.44
▸ MMP1 P03956 1/20 0.44
▸ MMP2 P08253 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL134524 0.97 TSHR (0.60) CNR2TSHRALDH1A1AOC3TRPA1
Water SCHEMBL4610445 0.94 CNR2 (0.58) CNR2TSHRALDH1A1AOC3TRPA1
Bromide SCHEMBL6760453 0.94 CNR2 (0.58) CNR2TSHRALDH1A1AOC3TRPA1
Hydrochloric Acid SCHEMBL2137949 0.94 CNR2 (0.58) CNR2TSHRALDH1A1AOC3TRPA1
Ammonia Solution, Strong SCHEMBL1348044 0.94 CNR2 (0.58) CNR2TSHRALDH1A1AOC3TRPA1
Bromide SCHEMBL11212819 0.94 CNR2 (0.58) CNR2TSHRALDH1A1AOC3TRPA1
SCHEMBL12049793 0.94 CNR2 (0.64) CNR2TSHRALDH1A1AOC3TRPA1
Chloromethane SCHEMBL27571631 0.88 CNR2 (0.59) CNR2TSHRALDH1A1AOC3TRPA1
SCHEMBL12763744 0.86 GRIN2D (0.53) CNR2TSHRALDH1A1AOC3TRPA1
Tetramethylammonium Ion SCHEMBL9770085 0.86 CNR2 (0.57) CNR2TSHRALDH1A1AOC3TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2302000-B1 CURABLE COMPOSITION AND CATALYST COMPOSITION KANEKA CORP (JP) 2016-11-16 — — EP disclosed
US-9051501-B2 Curable composition and catalyst composition KANEKA CORPORATION (JP) 2015-06-09 — — US disclosed
EP-2088173-B1 CURABLE COMPOSITION AND CATALYST COMPOSITION KANEKA CORP (JP) 2012-02-22 — — EP disclosed
EP-2302000-A1 Curable composition and catalyst composition KANEKA CORPORATION (JP) 2011-03-30 — — EP disclosed
US-20100041810-A1 CURABLE COMPOSITION AND CATALYST COMPOSITION KANEKA CORPORATION (JP) 2010-02-18 — — US disclosed
EP-2088173-A1 CURABLE COMPOSITION AND CATALYST COMPOSITION Kaneka Corporation (JP) 2009-08-12 — — EP disclosed
US-6618186-B2 Micro-electromechanical system TEXAS INSTRUMENTS INCORPORATED 2003-09-09 — — US disclosed
US-6586599-B1 Formating carbon-carbon bonds between carbocyclic halogen and organosilicon compounds in the presence of coordination catalysts, nitrogen compounds and bases; efficiency; catalysis UNIVERSITY OF NEW ORLEANS RESEARCH AND TECHNOLOGY FOUNDATION 2003-07-01 — — US disclosed
US-20020109903-A1 Micro-electromechanical system TEXAS INSTRUMENTS INCORPORATED 2002-08-15 — — US disclosed
WO-2001066248-A2 C-C AND C-N COUPLING CATALYST COMPRISING TRANSITION METAL AND CARBENE UNIVERSITY OF NEW ORLEANS RESEARCH AND TECHNOLOGY FOUNDATION (US) 2001-09-13 — — WO disclosed
EP-0633264-B1 Tertiary amino-aluminoxane halides ALBEMARLE CORP (US) 1999-03-03 — — EP disclosed
US-5466647-A Olefin polymerization catalyst ALBEMARLE CORPORATION (US) 1995-11-14 — — US disclosed
US-5412131-A Olefin polymerization catalyst ALBEMARLE CORPORATION (US) 1995-05-02 — — US disclosed
EP-0633264-A1 Tertiary amino-aluminoxane halides ALBEMARLE CORPORATION (US) 1995-01-11 — — EP disclosed