Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PDE8B | O95263 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26547634 | 1.00 | ATM (0.42) | ATMMEN1KMT2AALDH1A1USP2 | |
| SCHEMBL29550830 | 0.93 | ATM (0.44) | ATMMEN1KMT2AALDH1A1USP2 | |
| SCHEMBL4400854 | 0.93 | ATM (0.44) | ATMMEN1KMT2AALDH1A1USP2 | |
| SCHEMBL29550642 | 0.93 | ATM (0.44) | ATMMEN1KMT2AALDH1A1USP2 | |
| SCHEMBL6921210 | 0.91 | ATM (0.47) | ATMMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL16551790 | 0.91 | ATM (0.47) | ATMMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL6350025 | 0.91 | ATM (0.47) | ATMMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL24739379 | 0.88 | ATM (0.48) | ATMMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL29551182 | 0.88 | ATM (0.48) | ATMMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL29039237 | 0.88 | SMN1; SMN2 (0.41) | ATMMEN1KMT2AALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6878736-B1 | Histamine H3 receptor ligands | JAMES BLACK FOUNDATION LIMITED (GB) | 2005-04-12 | — | — | US | disclosed |