Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 20/20 | 1.00 |
| ▸ | KCNH2 | Q12809 | 12/20 | 0.87 |
| ▸ | MCHR2 | Q969V1 | 2/20 | 0.81 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6332974 | 0.93 | MCHR1 (1.00) | MCHR1KCNH2MCHR2CYP3A4 | |
| SCHEMBL6337941 | 0.90 | MCHR1 (1.00) | MCHR1KCNH2MCHR2CYP3A4 | |
| SCHEMBL6339556 | 0.88 | MCHR1 (1.00) | MCHR1KCNH2MCHR2CYP3A4 | |
| SCHEMBL6331147 | 0.88 | MCHR1 (0.90) | MCHR1KCNH2MCHR2CYP3A4 | |
| SCHEMBL6331022 | 0.87 | MCHR1 (0.89) | MCHR1KCNH2MCHR2CYP3A4 | |
| SCHEMBL6329899 | 0.87 | MCHR1 (0.95) | MCHR1KCNH2MCHR2CYP3A4 | |
| SCHEMBL6333446 | 0.87 | MCHR1 (1.00) | MCHR1KCNH2MCHR2CYP3A4 | |
| SCHEMBL6331238 | 0.86 | MCHR1 (0.86) | MCHR1KCNH2MCHR2CYP3A4 | |
| SCHEMBL6331213 | 0.86 | MCHR1 (0.83) | MCHR1KCNH2MCHR2CYP3A4 | |
| SCHEMBL6329905 | 0.84 | MCHR1 (1.00) | MCHR1KCNH2MCHR2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050209274-A1 | Antagonists of melanin concentrating hormone effects on the melanin concentrating hormone receptor | ABOTT LABORATORIES | 2005-09-22 | — | — | US | claimed |
| US-20050209274-A1 | Antagonists of melanin concentrating hormone effects on the melanin concentrating hormone receptor | ABOTT LABORATORIES | 2005-09-22 | — | — | US | disclosed |
| US-20050187387-A1 | Antagonists of melanin concentrating hormone effects on the melanin concentrating hormone receptor | ABBOTT LABORATORIES | 2005-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050209274-A1 | Antagonists of melanin concentrating hormone effects on the melanin concentrating hormone receptor | MCHR1, MCHR2, MC1R | MCHR1 1/4885KCNH2 1620/4885MCHR2 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.