Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.61 |
| ▸ | CA4 | P22748 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL1022163 | 0.92 | CA1 (0.73) | CA1CA4LMNATSHRTHPO | |
| Acetic Acid SCHEMBL891339 | 0.88 | CA1 (0.80) | CA1CA4LMNATSHRTHPO | |
| Acetic Acid SCHEMBL261008 | 0.88 | CA1 (0.80) | CA1CA4LMNATSHRTHPO | |
| Acetic Acid SCHEMBL8853430 | 0.84 | CA1 (0.73) | CA1CA4LMNATSHRTHPO | |
| Acetic Acid SCHEMBL10428030 | 0.84 | CA1 (0.73) | CA1CA4LMNATSHRTHPO | |
| Acetic Acid SCHEMBL3248576 | 0.84 | CA1 (0.73) | CA1CA4LMNATSHRTHPO | |
| Acetic Acid SCHEMBL10621969 | 0.84 | CA1 (0.73) | CA1CA4LMNATSHRTHPO | |
| Acetic Acid SCHEMBL11438862 | 0.84 | CA1 (0.82) | CA1CA4LMNATSHRTHPO | |
| Acetic Acid SCHEMBL29144396 | 0.84 | CA1 (0.73) | CA1CA4LMNATSHRTHPO | |
| Acetic Acid SCHEMBL37009 | 0.83 | CA1 (0.89) | CA1CA4LMNATSHRTHPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6936316-B2 | Ink-jet recording medium with an opaque or semi-opaque layer coated thereon, method for recording an image, and a recorded medium with at least one layer rendered clear or semi-opaque | PIXTERRA, INC. | 2005-08-30 | — | — | US | claimed |
| WO-2004052655-A1 | OPAQUE OR SEMI-OPAQUE LAYER COATED INK-JET RECORDING MEDIUM | PIXTERRA, INC. (US) | 2004-06-24 | — | — | WO | claimed |
| US-20040109958-A1 | Ink-jet recording medium with an opaque or semi-opaque layer coated thereon, method for recording an image, and a recorded medium with at least one layer rendered clear or semi-opaque | PIXTERRA, INC. | 2004-06-10 | — | — | US | claimed |