Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.70 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6334824 | 0.85 | IDO1 (0.65) | IDO1NOTUMCYP3A4CYP2D6CYP1A2 | |
| SCHEMBL29084862 | 0.82 | IDO1 (1.00) | IDO1NOTUMCYP3A4CYP2D6CYP1A2 | |
| SCHEMBL9451269 | 0.82 | IDO1 (0.57) | IDO1NOTUMCYP3A4CYP2D6CYP1A2 | |
| SCHEMBL23486498 | 0.79 | IDO1 (0.76) | IDO1NOTUMCYP3A4CYP2D6CYP1A2 | |
| SCHEMBL29758190 | 0.79 | IDO1 (0.76) | IDO1NOTUMCYP3A4CYP2D6CYP1A2 | |
| SCHEMBL30702138 | 0.79 | IDO1 (0.61) | IDO1NOTUMCYP3A4CYP2D6CYP1A2 | |
| SCHEMBL20360005 | 0.79 | IDO1 (0.61) | IDO1NOTUMCYP3A4CYP2D6CYP1A2 | |
| SCHEMBL16983194 | 0.79 | IDO1 (0.61) | IDO1NOTUMCYP3A4CYP2D6CYP1A2 | |
| SCHEMBL9451220 | 0.78 | CYP11B1 (0.57) | IDO1NOTUMCYP3A4CYP2D6CYP1A2 | |
| SCHEMBL11702033 | 0.78 | IDO1 (0.60) | IDO1NOTUMCYP3A4CYP2D6CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105873900-A | Process for diazotizing 2, 5-dichloroaniline | 孟山都技术公司 | 2016-08-17 | — | — | CN | disclosed |
| US-6960601-B2 | Preparation and use of imidazole derivatives for treatment of obesity | BAYER PHARMACEUTICALS CORPORATION (US) | 2005-11-01 | — | — | US | disclosed |