Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 13/20 | 0.57 |
| ▸ | ITGA4 | P13612 | 13/20 | 0.57 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6340843 | 0.92 | ITGB1 (0.57) | ITGB1ITGA4ITGB7SMN1; SMN2KMT2A | |
| SCHEMBL6343632 | 0.89 | ITGB1 (0.60) | ITGB1ITGA4ITGB7SMN1; SMN2KMT2A | |
| SCHEMBL6353994 | 0.89 | ITGB1 (0.59) | ITGB1ITGA4ITGB7SMN1; SMN2KMT2A | |
| SCHEMBL6353843 | 0.86 | ITGB1 (0.64) | ITGB1ITGA4ITGB7SMN1; SMN2KMT2A | |
| SCHEMBL6354005 | 0.85 | ITGB1 (0.56) | ITGB1ITGA4ITGB7SMN1; SMN2KMT2A | |
| SCHEMBL6344233 | 0.85 | ITGB1 (0.59) | ITGB1ITGA4ITGB7SMN1; SMN2POLB | |
| SCHEMBL6340839 | 0.85 | ITGB1 (0.55) | ITGB1ITGA4ITGB7SMN1; SMN2KMT2A | |
| SCHEMBL6343898 | 0.81 | ITGB1 (0.63) | ITGB1ITGA4ITGB7SMN1; SMN2KMT2A | |
| SCHEMBL6788710 | 0.81 | ITGB1 (0.51) | ITGB1ITGA4ITGB7SMN1; SMN2KMT2A | |
| SCHEMBL6786166 | 0.80 | ITGB1 (0.61) | ITGB1ITGA4ITGB7SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6949534-B2 | Cell adhesion inhibitors | BIOGEN IDEC MA INC. (US) | 2005-09-27 | — | — | US | claimed |