Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 20/20 | 0.52 |
| ▸ | KIT | P10721 | 2/20 | 0.50 |
| ▸ | FLT3 | P36888 | 2/20 | 0.50 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6346268 | 0.89 | PDGFRB (0.53) | PDGFRBKITFLT3PDGFRA | |
| SCHEMBL6339726 | 0.88 | PDGFRB (0.68) | PDGFRBKITFLT3PDGFRA | |
| SCHEMBL6345610 | 0.86 | PDGFRB (0.65) | PDGFRBKITFLT3 | |
| SCHEMBL6344527 | 0.86 | PDGFRB (0.65) | PDGFRBKITFLT3 | |
| SCHEMBL6334880 | 0.86 | PDGFRB (0.69) | PDGFRBKITFLT3 | |
| SCHEMBL6339712 | 0.85 | PDGFRB (0.70) | PDGFRBKITFLT3 | |
| SCHEMBL6344392 | 0.84 | PDGFRB (0.71) | PDGFRBKITFLT3 | |
| SCHEMBL6345627 | 0.84 | PDGFRB (0.61) | PDGFRBKITFLT3PDGFRA | |
| SCHEMBL6336465 | 0.83 | PDGFRB (0.61) | PDGFRBKITFLT3PDGFRA | |
| SCHEMBL6335032 | 0.82 | PDGFRB (0.60) | PDGFRBKITFLT3PDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6960580-B2 | Nitrogenous heterocyclic substituted quinoline compounds | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2005-11-01 | — | — | US | claimed |