⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6336498 | 0.91 | MEN1 (0.35) | — | |
| SCHEMBL6635590 | 0.90 | — | — | |
| SCHEMBL6341509 | 0.89 | KDM4E (0.33) | — | |
| SCHEMBL6339651 | 0.89 | KCNH2 (0.40) | — | |
| SCHEMBL6339259 | 0.89 | — | — | |
| SCHEMBL6339826 | 0.86 | MEN1 (0.34) | — | |
| SCHEMBL6339944 | 0.85 | — | — | |
| SCHEMBL6707971 | 0.82 | KCNH2 (0.48) | — | |
| SCHEMBL6345362 | 0.81 | — | — | |
| SCHEMBL6631513 | 0.81 | MEN1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6924283-B2 | 4-thioxo-4,7-dihydro-thieno[2,3-b]pyridine-5-carbothioamides as antiviral agents | PFIZER (US) | 2005-08-02 | — | — | US | claimed |
| EP-1421088-A1 | 4-THIOXO-4,7-DIHYDRO-THIENO 2,3-B]PYRIDINE-5-CARBOTHIOAMIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2004-05-26 | — | — | EP | claimed |
| US-20030100536-A1 | 4-Thioxo-4,7-dihydro-thieno[2,3-b]pyridine-5-carbothioamides as antiviral agents | PHARMACIA & UPJOHN COMPANY | 2003-05-29 | — | — | US | claimed |
| WO-2003020730-A1 | 4-THIOXO-4,7-DIHYDRO-THIENO[2,3-B]PYRIDINE-5-CARBOTHIOAMIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2003-03-13 | — | — | WO | claimed |
| US-6924283-B2 | 4-thioxo-4,7-dihydro-thieno[2,3-b]pyridine-5-carbothioamides as antiviral agents | PFIZER (US) | 2005-08-02 | — | — | US | disclosed |
| EP-1421088-A1 | 4-THIOXO-4,7-DIHYDRO-THIENO 2,3-B]PYRIDINE-5-CARBOTHIOAMIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2004-05-26 | — | — | EP | disclosed |
| US-20030100536-A1 | 4-Thioxo-4,7-dihydro-thieno[2,3-b]pyridine-5-carbothioamides as antiviral agents | PHARMACIA & UPJOHN COMPANY | 2003-05-29 | — | — | US | disclosed |
| WO-2003020730-A1 | 4-THIOXO-4,7-DIHYDRO-THIENO[2,3-B]PYRIDINE-5-CARBOTHIOAMIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2003-03-13 | — | — | WO | disclosed |