Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.39 |
| ▸ | FDPS | P14324 | 3/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.38 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.37 |
| ▸ | ADH1B | P00325 | 1/20 | 0.36 |
| ▸ | ADH1C | P00326 | 1/20 | 0.36 |
| ▸ | ADH1A | P07327 | 1/20 | 0.36 |
| ▸ | ADH4 | P08319 | 1/20 | 0.36 |
| ▸ | ADH7 | P40394 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | LAP3 | P28838 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10778522 | 1.00 | MAPT (0.42) | MAPTGPR84FDPSFFAR1LMNA | |
| SCHEMBL231625 | 1.00 | MAPT (0.42) | MAPTGPR84FDPSFFAR1LMNA | |
| SCHEMBL8743261 | 1.00 | MAPT (0.42) | MAPTGPR84FDPSFFAR1LMNA | |
| SCHEMBL6436761 | 1.00 | MAPT (0.42) | MAPTGPR84FDPSFFAR1LMNA | |
| SCHEMBL8743266 | 1.00 | MAPT (0.42) | MAPTGPR84FDPSFFAR1LMNA | |
| SCHEMBL362511 | 1.00 | MAPT (0.42) | MAPTGPR84FDPSFFAR1LMNA | |
| SCHEMBL164412 | 1.00 | MAPT (0.42) | MAPTGPR84FDPSFFAR1LMNA | |
| SCHEMBL230915 | 1.00 | MAPT (0.42) | MAPTGPR84FDPSFFAR1LMNA | |
| SCHEMBL8743022 | 1.00 | MAPT (0.42) | MAPTGPR84FDPSFFAR1LMNA | |
| SCHEMBL355716 | 1.00 | MAPT (0.42) | MAPTGPR84FDPSFFAR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6878794-B1 | Urethane resins | TENNANT COMPANY (US) | 2005-04-12 | — | — | US | disclosed |
| US-6465598-B2 | ADDING WATER TO A POLYKETIMINE FUNCTIONALIZED POLYURETHANE RESIN TO DEBLOCK THE AMINE AND REMOVING KETONE, THUS FORMING AMINE-TERMINATED POLYURETHANE RESIN | TENNANT COMPANY | 2002-10-15 | — | — | US | disclosed |
| US-20010007900-A1 | Adding water to a polyketimine functionalized polyurethane resin to deblock the amine and removing ketone, thus forming amine-terminated polyurethane resin | JPMORGAN CHASE BANK, N.A., AS ADMINISTRATIVE AGENT | 2001-07-12 | — | — | US | disclosed |
| US-6218500-B1 | AMINE-TERMINATED URETHANE OLIGOMER COMPOSITIONS ARE DESCRIBED THAT INCLUDE VERY HIGH OLIGOMER CONCENTRATIONS. | TENNANT COMPANY | 2001-04-17 | — | — | US | disclosed |
| EP-0319841-B1 | HIGH PERFORMANCE AQUEOUS URETHANE EPOXY COATINGS | Tennant Company (US) | 1993-09-29 | — | — | EP | disclosed |
| US-5227414-A | For concrete floors, endcapping urethane with ketimine, hydrolysis, reaction with epoxy | TENNANT COMPANY (US) | 1993-07-13 | — | — | US | disclosed |
| US-4861825-A | Aqueous urethane coatings | TENNANT COMPANY (US) | 1989-08-29 | — | — | US | disclosed |
| EP-0319841-A2 | High performance aqueous urethane epoxy coatings | Tennant Company (US) | 1989-06-14 | — | — | EP | disclosed |
| US-4772643-A | CHAIN EXTENSION, CROSSLINKING, BLOCKING AGENTS | TENNANT COMPANY (US) | 1988-09-20 | — | — | US | disclosed |
| CN-85102119-A | EFFICIENT OSCILLATING EJECTOR | — | 1987-03-11 | — | — | CN | disclosed |
| US-4513112-A | POLYETHYLENE OXIDE CONTAINING ISOCYANATE, COLLOIDAL SILICA | LORD CORPORATION (US) | 1985-04-23 | — | — | US | disclosed |
| US-4444846-A | POLYURETHANES | LORD CORPORATION (US) | 1984-04-24 | — | — | US | disclosed |
| US-4409383-A | CURED POLYETHERURETHANE COPOLYMER; REVERSIBLE TRANSPARENT | LORD CORPORATION (US) | 1983-10-11 | — | — | US | disclosed |
| US-3948665-A | Laminates for the manufacture of flexographic printing plates comprising photocrosslinkable reaction product of saturated polyester glycol, diisocyanate, and diol | BASF AKTIENGESELLSCHAFT (DT) | 1976-04-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010007900-A1 | Adding water to a polyketimine functionalized polyurethane resin to deblock the amine and removing ketone, thus forming amine-terminated polyurethane resin | PUF60, RAD23B, XRCC5 | MAPT 265/4885GPR84 1612/4885FDPS 2574/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.