Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 6/20 | 0.68 |
| ▸ | HTR2A | P28223 | 2/20 | 0.54 |
| ▸ | RET | P07949 | 1/20 | 0.48 |
| ▸ | ACP3 | P15309 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29633441 | 1.00 | ANPEP (0.68) | ANPEPHTR2ARETACP3IDO1 | |
| SCHEMBL113822 | 0.84 | HTR2A (0.73) | ANPEPHTR2ARETACP3IDO1 | |
| SCHEMBL31165889 | 0.84 | HTR2A (0.73) | ANPEPHTR2ARETACP3IDO1 | |
| SCHEMBL28518727 | 0.81 | ANPEP (1.00) | ANPEPHTR2A | |
| SCHEMBL18999729 | 0.81 | ANPEP (1.00) | ANPEPHTR2A | |
| SCHEMBL9385590 | 0.78 | ACP3 (0.48) | ANPEPHTR2ARETACP3IDO1 | |
| SCHEMBL10581227 | 0.77 | CA1 (0.46) | ANPEPHTR2ARETACP3IDO1 | |
| SCHEMBL10642897 | 0.77 | HTR2A (0.56) | ANPEPHTR2ARETACP3IDO1 | |
| SCHEMBL7124003 | 0.77 | ACP3 (0.47) | ANPEPHTR2ARETACP3IDO1 | |
| SCHEMBL8901794 | 0.77 | ACP3 (0.47) | ANPEPHTR2ARETACP3IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021038889-A1 | METHOD FOR PRODUCING HETEROCYCLIDENE ACETAMIDE DERIVATIVE | 持田製薬株式会社 | 2021-03-04 | — | — | WO | disclosed |
| EP-2752410-B1 | HETEROCYCLE DERIVATIVE HAVING PGD2 RECEPTOR ANTAGONIST ACTIVITY | SHIONOGI & CO (JP) | 2016-08-31 | — | — | EP | disclosed |
| EP-2952503-A1 | HIV REPLICATION INHIBITOR | Shionogi & Co., Ltd. (JP) | 2015-12-09 | — | — | EP | disclosed |
| WO-2015156421-A1 | DIHYDROTHIAZINE AND DIHYDROOXAZINE DERIVATIVES HAVING BACE1 INHIBITORY ACTIVITY | SHIONOGI & CO., LTD. (JP) | 2015-10-15 | — | — | WO | disclosed |
| EP-2772480-A1 | HIV REPLICATION INHIBITOR | Shionogi & Co., Ltd. (JP) | 2014-09-03 | — | — | EP | disclosed |
| EP-2752410-A1 | HETEROCYCLE DERIVATIVE HAVING PGD2 RECEPTOR ANTAGONIST ACTIVITY | Shionogi & Co., Ltd. (JP) | 2014-07-09 | — | — | EP | disclosed |
| WO-2013001830-A1 | NUCLEOSIDE ANTIBIOTIC DERIVATIVE | 国立大学法人北海道大学 (JP) | 2013-01-03 | — | — | WO | disclosed |
| US-6844368-B1 | Compounds useful in pain management | ASTRAZENECA CANADA INC. (CA) | 2005-01-18 | — | — | US | disclosed |
| EP-1140790-A1 | NOVEL OXO-AMINOTETRALIN COMPOUNDS USEFUL IN PAIN MANAGEMENT | AstraZeneca AB (SE) | 2001-10-10 | — | — | EP | disclosed |
| EP-1140790-A1 | NOVEL OXO-AMINOTETRALIN COMPOUNDS USEFUL IN PAIN MANAGEMENT | AstraZeneca AB (SE) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000037426-A1 | NOVEL OXO-AMINOTETRALIN COMPOUNDS USEFUL IN PAIN MANAGEMENT | ASTRAZENECA AB (SE) | 2000-06-29 | — | — | WO | disclosed |
| WO-2000037426-A1 | NOVEL OXO-AMINOTETRALIN COMPOUNDS USEFUL IN PAIN MANAGEMENT | ASTRAZENECA AB (SE) | 2000-06-29 | — | — | WO | disclosed |
| US-5196454-A | METHOD OF TREATING DISORDERS OF THE DOPAMINERGIC SYSTEMS USING 2,5-DIAMINOTETRALINES | BOEHRINGER INGELHEIM KG (DE) | 1993-03-23 | — | — | US | disclosed |
| US-3970650-A | DRUG INTERMEDIATE | A. CHRISTIAENS SOCIETE ANONYME (BE) | 1976-07-20 | — | — | US | disclosed |