Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 14/20 | 0.74 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.59 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.59 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6326894 | 1.00 | ADORA2A (0.74) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL6052019 | 1.00 | ADORA2A (0.74) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL6326890 | 1.00 | ADORA2A (0.74) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL6347121 | 1.00 | ADORA2A (0.74) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL6052013 | 1.00 | ADORA2A (0.74) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL6321747 | 0.93 | ADORA2A (0.72) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL6321743 | 0.93 | ADORA2A (0.72) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL6913464 | 0.91 | ADORA2A (0.78) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL6913460 | 0.91 | ADORA2A (0.78) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL6327867 | 0.91 | ADORA2A (0.78) | ADORA2AADORA3ADORA1ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6900309-B1 | Purine derivatives | PFIZER INC (US) | 2005-05-31 | — | — | US | disclosed |