Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 7/20 | 0.61 |
| ▸ | RAB9A | P51151 | 6/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.55 |
| ▸ | MEN1 | O00255 | 6/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4875896 | 0.82 | ABL1 (0.70) | ABL1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL4787902 | 0.79 | ABL1 (0.74) | ABL1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL2020280 | 0.79 | ABL1 (0.73) | ABL1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL28200307 | 0.77 | ABL1 (0.76) | ABL1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL6350141 | 0.77 | ABL1 (0.60) | ABL1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL15688730 | 0.76 | ABL1 (0.74) | ABL1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL9893009 | 0.76 | ABL1 (1.00) | ABL1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL12527532 | 0.76 | ABL1 (0.74) | ABL1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL10699534 | 0.76 | ABL1 (0.73) | ABL1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL4863807 | 0.75 | ABL1 (0.60) | ABL1RAB9AKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1587800-A1 | THIAZOLE DERIVATIVES AND THEIR USE AS VAP-1 INHIBITORS | Astellas Pharma Inc. (JP) | 2005-10-26 | — | — | EP | disclosed |
| WO-2004067521-A1 | THIAZOLE DERIVATIVES AND THEIR USE AS VAP-1 INHIBITORS | ASTELLAS PHARMA INC. (JP) | 2004-08-12 | — | — | WO | disclosed |