Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6348804 | 0.77 | GAA (0.37) | GAA | |
| SCHEMBL6348809 | 0.77 | GAA (0.37) | GAA | |
| SCHEMBL23998492 | 0.77 | GAA (0.37) | GAA | |
| SCHEMBL7805815 | 0.75 | GAA (0.35) | GAA | |
| SCHEMBL9656486 | 0.66 | GAA (0.42) | GAA | |
| SCHEMBL18253 | 0.66 | GAA (0.42) | GAA | |
| SCHEMBL13518714 | 0.66 | — | — | |
| SCHEMBL8648502 | 0.64 | GAA (0.41) | GAA | |
| SCHEMBL452395 | 0.64 | — | — | |
| SCHEMBL2266278 | 0.64 | GAA (0.41) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6960688-B2 | Use of compounds for the elevation of pyruvate dehydrogenase activity | ASTRAZENECA AB (SE) | 2005-11-01 | — | — | US | disclosed |
| US-6498275-B1 | Use of compounds for the elevation of pyruvate dehydrogenase activity | ASTRAZENECA AB (SE) | 2002-12-24 | — | — | US | disclosed |