Pirnabine

Pirnabine

SCHEMBL635078

CC(=O)Oc1cc(C)cc2c1C1=C(CCC(C)C1)C(C)(C)O2

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ CNR2 P34972 8/20 0.67
▸ CNR1 P21554 5/20 0.67
▸ MEN1 O00255 1/20 0.67
▸ GAA P10253 1/20 0.67
▸ KMT2A Q03164 1/20 0.67
▸ ELANE P08246 1/20 0.34
▸ ESR1 P03372 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11737598 0.80 CNR2 (0.42) CNR2CNR1MEN1GAAKMT2A
SCHEMBL31544851 0.80 CNR2 (1.00) CNR2CNR1MEN1GAAKMT2A
SCHEMBL11639037 0.80 CNR2 (1.00) CNR2CNR1MEN1GAAKMT2A
SCHEMBL31545774 0.80 CNR2 (1.00) CNR2CNR1MEN1GAAKMT2A
SCHEMBL11739647 0.78 CNR2 (0.51) CNR2CNR1MEN1GAAKMT2A
SCHEMBL22783274 0.68 CNR2 (0.78) CNR2CNR1MEN1GAAKMT2A
SCHEMBL31544945 0.67 CNR2 (0.67) CNR2CNR1MEN1GAAKMT2A
SCHEMBL31395335 0.66 CNR2 (0.72) CNR2CNR1MEN1GAAKMT2A
SCHEMBL16124349 0.65 CNR2 (0.94) CNR2CNR1MEN1GAAKMT2A
SCHEMBL31545931 0.65 CNR2 (0.57) CNR2CNR1MEN1GAAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 213 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260124148-A1 POLYPEPTIDE FORMULATIONS FOR ORAL DELIVERY BHAMIS RES LABORATORY PVT LTD (IN) 2026-05-07 — — US claimed
US-12533321-B2 Polypeptide formulations for oral delivery Bhami's Research Laboratory, Pvt. Ltd. (IN) 2026-01-27 — — US claimed
US-20250360137-A1 ENHANCEMENT OF THE EFFICACY OF SEROTONERGIC PSYCHEDELIC DRUGS IN THE TREATMENT OR PREVENTION OF CERTAIN NEUROPSYCHIATRIC DISORDERS THROUGH INHIBITION OF TYPE-9 PHOSPHODIESTERASES FREEDOM BIOSCIENCES INC (US) 2025-11-27 — — US claimed
EP-4618980-A1 ENHANCEMENT OF THE EFFICACY OF SEROTONERGIC PSYCHEDELIC DRUGS IN THE TREATMENT OR PREVENTION OF CERTAIN NEUROPSYCHIATRIC DISORDERS THROUGH INHIBITION OF TYPE-9 PHOSPHODIESTERASES Freedom Biosciences, Inc. (US) 2025-09-24 — — EP claimed
EP-4601623-A1 POLYPEPTIDE FORMULATIONS FOR ORAL DELIVERY Bhami's Research Laboratory, Pvt. Ltd. (IN) 2025-08-20 — — EP claimed
WO-2024107445-A1 ENHANCEMENT OF THE EFFICACY OF SEROTONERGIC PSYCHEDELIC DRUGS IN THE TREATMENT OR PREVENTION OF CERTAIN NEUROPSYCHIATRIC DISORDERS THROUGH INHIBITION OF TYPE-9 PHOSPHODIESTERASES FREEDOM BIOSCIENCES, INC. (US) 2024-05-23 — — WO claimed
WO-2024079738-A1 ORAL POLYPEPTIDE FORMULATIONS Bhami's Research Laboratory, Pvt. Ltd. (IN) 2024-04-18 — — WO claimed
US-20240122860-A1 POLYPEPTIDE FORMULATIONS FOR ORAL DELIVERY Bhami's Research Laboratory, Pvt. Ltd. (IN) 2024-04-18 — — US claimed
WO-2024079739-A1 POLYPEPTIDE FORMULATIONS FOR ORAL DELIVERY Bhami's Research Laboratory, Pvt. Ltd. (IN) 2024-04-18 — — WO claimed
US-20240122847-A1 ORAL POLYPEPTIDE FORMULATIONS Bhami's Research Laboratory, Pvt. Ltd. (IN) 2024-04-18 — — US claimed
US-8268352-B2 Modified release composition for highly soluble drugs TORRENT PHARMACEUTICALS LIMITED (IN) 2012-09-18 — — US claimed
US-8263125-B2 Dosage form for high dose-high solubility active ingredients that provides for immediate release and modified release of the active ingredients TORRENT PHARMACEUTICALS LIMITED (IN) 2012-09-11 — — US claimed
US-20100226943-A1 SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL UNIVERSITY OF FLORIDA (US) 2010-09-09 — — US claimed
EP-1954244-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY Scidose, Llc (US) 2008-08-13 — — EP claimed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 — — WO claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 — — US claimed
US-20060024365-A1 Novel dosage form VAYA NAVIN 2006-02-02 — — US claimed
US-20060018933-A1 Novel drug delivery system TORRENT PHARMACEUTICALS LIMITED (IN) 2006-01-26 — — US claimed
US-20060018934-A1 Novel drug delivery system TORRENT PHARMACEUTICALS LIMITED (IN) 2006-01-26 — — US claimed
US-6919076-B1 Conjugates of agents and transglutaminase substrate linking molecules PERICOR SCIENCE, INC. (US) 2005-07-19 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12533321-B2 Polypeptide formulations for oral delivery PTMS, IAPP, IGF1R CNR2 1603/4885CNR1 1998/4885MEN1 2575/4885
US-20250360137-A1 ENHANCEMENT OF THE EFFICACY OF SEROTONERGIC PSYCHEDELIC DRUGS IN THE TREATMENT OR PREVENTION OF CERTAIN NEUROPSYCHIATRIC DISORDERS THROUGH INHIBITION OF TYPE-9 PHOSPHODIESTERASES PDE9A, PDE3A, PDE2A CNR2 204/4885CNR1 221/4885MEN1 2211/4885
US-20260124148-A1 POLYPEPTIDE FORMULATIONS FOR ORAL DELIVERY GLP1R, TTR, IAPP CNR2 1385/4885CNR1 1892/4885MEN1 1288/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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