Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | AHR | P35869 | 3/20 | 0.53 |
| ▸ | GABRP | O00591 | 4/20 | 0.50 |
| ▸ | GABRD | O14764 | 4/20 | 0.50 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.50 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.50 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.50 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.50 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.50 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.50 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.50 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29886872 | 1.00 | MAPT (0.59) | MAPTKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL67700 | 1.00 | MAPT (0.59) | MAPTKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL25620895 | 0.96 | MAPT (0.55) | MAPTKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL30038021 | 0.94 | MAPT (0.53) | MAPTKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL16990760 | 0.94 | MAPT (0.53) | MAPTKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL2802294 | 0.92 | MAPT (0.52) | MAPTKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL1637337 | 0.89 | MAPT (0.49) | MAPTKDM4EALDH1A1HPGDSMN1; SMN2 | |
| Aniline SCHEMBL28503615 | 0.89 | NPC1 (0.62) | MAPTKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL19561508 | 0.89 | PIM1 (0.52) | MAPTKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL258689 | 0.89 | PIM1 (0.55) | MAPTSMN1; SMN2NPC1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1441011-B1 | Energy transfer dye containing an aromatic-substituted xanthene dye as donor dye and/or acceptor dye | LIFE TECHNOLOGIES CORP (US) | 2012-02-22 | — | — | EP | disclosed |