Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 12/20 | 0.55 |
| ▸ | PDE4A | P27815 | 11/20 | 0.48 |
| ▸ | PDE4C | Q08493 | 11/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 11/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6352103 | 0.95 | PDE4B (0.50) | PDE4BPDE4APDE4CPDE4DHSD17B10 | |
| SCHEMBL1465431 | 0.92 | PDE4B (0.46) | PDE4BPDE4APDE4CPDE4DSIRT2 | |
| SCHEMBL17106559 | 0.90 | PDE4B (0.48) | PDE4BPDE4APDE4CPDE4DKDM4E | |
| SCHEMBL20028131 | 0.87 | SMN1; SMN2 (0.48) | PDE4BPDE4APDE4CPDE4DHSD17B10 | |
| SCHEMBL20028829 | 0.83 | SMN1; SMN2 (0.45) | PDE4BHSD17B10KDM4ECYP1A2CYP3A4 | |
| SCHEMBL28665078 | 0.82 | PDE4B (0.51) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL77276 | 0.82 | PDE4B (0.59) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL3165771 | 0.81 | PDE4B (0.63) | PDE4BPDE4APDE4CPDE4DMAPK1 | |
| SCHEMBL21874188 | 0.79 | S1PR5 (0.40) | PDE4B | |
| SCHEMBL13526248 | 0.77 | PDE4B (0.58) | PDE4BPDE4APDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050239841-A1 | New compounds | BIOVITRUM AB (SE) | 2005-10-27 | — | — | US | disclosed |
| WO-2005051381-A1 | Substituted urea-octatydroindols as antagonists of melanin concentrating hormone receptor 1 (MCH1R) | BIOVITRUM AB (SE) | 2005-06-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050239841-A1 | New compounds | MCHR1, NPY1R, HCRTR1 | PDE4B 815/4885PDE4A 897/4885PDE4C 1030/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.