⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8501614 | 0.79 | — | — | |
| SCHEMBL14008328 | 0.78 | — | — | |
| SCHEMBL27854452 | 0.71 | — | — | |
| SCHEMBL2058388 | 0.70 | — | — | |
| SCHEMBL28800803 | 0.69 | GABRR1 (0.35) | — | |
| Isopropyl Alcohol SCHEMBL11146748 | 0.67 | CA12 (0.62) | — | |
| SCHEMBL17472963 | 0.67 | CA12 (0.62) | — | |
| SCHEMBL10594176 | 0.67 | GABRR1 (0.30) | — | |
| SCHEMBL28034763 | 0.67 | CA12 (0.50) | — | |
| SCHEMBL11738050 | 0.66 | CA12 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6936593-B1 | Method of down-regulating gene expression | HYBRIDON, INC. (US) | 2005-08-30 | — | — | US | disclosed |
| US-20040033980-A1 | Method of down-regulating gene expression | HYBRIDON, INC. | 2004-02-19 | — | — | US | disclosed |
| US-6645943-B1 | Method of down-regulating gene expression | HYBRIDON, INC. | 2003-11-11 | — | — | US | disclosed |
| US-6608035-B1 | Orally administering to mammal oligonucleotide of 15 to 30 nucleotides, comprising phosphorothioate linkages between nucleosides and 2'-O-alkoxyalkyl-ribonucleotides at each end, whereby oligonucleotide is intact in liver and kidney tissue | HYBRIDON, INC. | 2003-08-19 | — | — | US | disclosed |