Carbon Monoxide

Carbon Monoxide

SCHEMBL6353577

CCCCCCCCOc1cc2ccc3cccnc3c2nc1Cl.[C]=O.[C]=O.[C]=O.[Re]

nearest known ligand 0.46

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCHR1 Q99705 3/20 0.46
TLR8 Q9NR97 2/20 0.43
NPC1 O15118 2/20 0.42
RAB9A P51151 2/20 0.42
KDM4E B2RXH2 7/20 0.42
MAPT P10636 5/20 0.42
LMNA P02545 4/20 0.42
NPSR1 Q6W5P4 2/20 0.42
GAA P10253 2/20 0.42
ALDH1A1 P00352 1/20 0.42
POLB P06746 1/20 0.42
HPGD P15428 2/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C19 P33261 1/20 0.41
PDE5A O76074 2/20 0.41
PDE4A P27815 2/20 0.41
PDE4B Q07343 2/20 0.41
PDE4C Q08493 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Carbon Monoxide SCHEMBL6353603 0.80 CNR2 (0.38) MCHR1TLR8NPC1RAB9AKDM4E
SCHEMBL3847754 0.78 TLR8 (0.50) MCHR1TLR8NPC1RAB9AKDM4E
SCHEMBL18691791 0.75 MCHR1 (0.67) MCHR1NPC1RAB9AKDM4EMAPT
SCHEMBL16114005 0.75 MCHR1 (0.67) MCHR1NPC1RAB9AKDM4EMAPT
SCHEMBL9632939 0.75 MCHR1 (0.67) MCHR1NPC1RAB9AKDM4EMAPT
SCHEMBL10647335 0.75 MCHR1 (0.67) MCHR1NPC1RAB9AKDM4EMAPT
SCHEMBL6350483 0.75 CCR1 (0.51) MCHR1NPC1RAB9AKDM4EMAPT
SCHEMBL9568616 0.73 MAPT (0.66) MCHR1NPC1RAB9AKDM4EMAPT
SCHEMBL28940847 0.72 MEN1 (0.50) MCHR1TLR8NPC1RAB9AMAPT
SCHEMBL9243789 0.71 MCHR1 (0.52) MCHR1NPC1RAB9AKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6929873-B2 Electroluminescent device using metal coordination compound CANON KABUSHIKI KAISHA (JP) 2005-08-16 US disclosed
US-20040013905-A1 Electroluminescent device using metal coordination compound CANON KABUSHIKI KAISHA (JP) 2004-01-22 US disclosed