SCHEMBL6356249

SCHEMBL6356249

CCCCCCCN(CCc1cccc(OC(C)(CC)C(=O)O)c1)C(=O)Nc1ccc(C(C)C)cc1

nearest known ligand 0.56

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 14/20 0.56
PPARG P37231 12/20 0.56
PPARD Q03181 3/20 0.54
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA9 Q16790 1/20 0.41
MMP2 P08253 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6359747 1.00 PPARA (0.56) PPARAPPARGPPARDCA12CA1
SCHEMBL6359783 1.00 PPARA (0.56) PPARAPPARGPPARDCA12CA1
SCHEMBL6362301 0.92 PPARA (0.64) PPARAPPARGPPARDCA12CA1
SCHEMBL6359007 0.91 PPARA (0.61) PPARAPPARGPPARDCA12CA1
SCHEMBL6364127 0.91 PPARA (0.58) PPARAPPARGPPARDCA12CA1
SCHEMBL6361165 0.91 PPARA (0.61) PPARAPPARGPPARDCA12CA1
SCHEMBL6361171 0.91 PPARA (0.61) PPARAPPARGPPARDCA12CA1
SCHEMBL6363401 0.91 PPARA (0.58) PPARAPPARGPPARDCA12CA1
SCHEMBL6363531 0.91 PPARA (0.61) PPARAPPARGPPARDCA12CA1
SCHEMBL6364111 0.90 PPARA (0.60) PPARAPPARGPPARDCA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2004520397-A 2004-07-08 JP claimed
EP-1372632-A1 PROLIFERATIVE ACTIVATOR RECEPTOR (PPAR) COMPOUNDS Pfizer Products Inc. (US) 2004-01-02 EP claimed
US-20020169192-A1 PPAR compounds HAYWARD CHERYL M (US) 2002-11-14 US claimed
WO-2002064130-A1 PROLIFERATIVE ACTIVATOR RECEPTOR (PPAR) COMPOUNDS PFIZER PRODUCTS INC. (US) 2002-08-22 WO claimed
US-20050075377-A1 PPAR compounds PFIZER INC 2005-04-07 US disclosed
US-6852161-B2 METHOD OF FABRICATING GROUP-III NITRIDE SEMICONDUCTOR CRYSTAL, METHOD OF FABRICATING GALLIUM NITRIDE-BASED COMPOUND SEMICONDUCTOR, GALLIUM NITRIDE-BASED COMPOUND SEMICONDUCTOR, GALLIUM NITRIDE-BASED COMPOUND SEMICONDUCTOR LIGHT-EMITTING DEVICE, AND LIGHT SOURCE USING THE SEMICONDUCTOR LIGHT-EMITTING DEVICE SHOWA DENKO K.K. (JP) 2005-02-08 US disclosed
EP-1372632-A1 PROLIFERATIVE ACTIVATOR RECEPTOR (PPAR) COMPOUNDS Pfizer Products Inc. (US) 2004-01-02 EP disclosed
US-20020169192-A1 PPAR compounds HAYWARD CHERYL M (US) 2002-11-14 US disclosed
US-20020155712-A1 Method of fabricating group-III nitride semiconductor crystal, method of fabricating gallium nitride-based compound semiconductor, gallium nitride-based compound semiconductor, gallium nitride-based compound semiconductor light-emitting device, and light source using the semiconductor light-emitting device TOYODA GOSEI CO., LTD. (JP) 2002-10-24 US disclosed
WO-2002064130-A1 PROLIFERATIVE ACTIVATOR RECEPTOR (PPAR) COMPOUNDS PFIZER PRODUCTS INC. (US) 2002-08-22 WO disclosed
WO-2002017369-A1 METHOD OF FABRICATING GROUP-III NITRIDE SEMICONDUCTOR CRYSTAL, METHO OF FABRICATING GALLIUM NITRIDE-BASED COMPOUND SEMICONDUCTOR, GALLIUM NITRIDE-BASED COMPOUND SEMICONDUCTOR, GALLIUM NITRIDE-BASED COMPOUND SEMICONDUCTOR LIGHT-EMITTING DEVICE, AND LIGHT SOURCE USING THE SEMICONDUCTOR LIGHT-EMITTING DEVICE SHOWA DENKO K.K. (JP) 2002-02-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020169192-A1 PPAR compounds PPARA, PPARG, PPARD PPARA 1/4885PPARG 2/4885PPARD 3/4885
US-20050075377-A1 PPAR compounds PPARA, PPARG, PPARD PPARA 1/4885PPARG 2/4885PPARD 3/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.