Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A3 | O15427 | 2/20 | 0.50 |
| ▸ | PDE5A | O76074 | 1/20 | 0.49 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.43 |
| ▸ | PLA2G2A | P14555 | 4/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.43 |
| ▸ | MCTS1 | Q9ULC4 | 1/20 | 0.43 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5118969 | 0.82 | PDE5A (0.71) | SLC16A3PDE5APLA2G2APTGDR2SLC16A1 | |
| SCHEMBL5118966 | 0.77 | PDE5A (0.61) | PDE5APLA2G2APTGDR2MAPTPLA2G1B | |
| SCHEMBL929883 | 0.74 | SLC16A3 (0.74) | SLC16A3SLC16A1MCTS1 | |
| SCHEMBL1120899 | 0.74 | PDE5A (0.58) | PDE5ASLC22A12PLA2G2APTGDR2PLA2G10 | |
| SCHEMBL1651401 | 0.73 | SLC16A3 (0.62) | SLC16A3PLA2G2ASLC16A1MCTS1 | |
| SCHEMBL1651049 | 0.72 | CNR1 (0.57) | SLC16A3CNR2CNR1PTGER4 | |
| SCHEMBL927453 | 0.72 | PDE5A (0.56) | SLC16A3PDE5APLA2G2APTGDR2PLA2G1B | |
| SCHEMBL13931862 | 0.71 | HDAC1 (0.50) | PDE5APLA2G2AALDH1A1GAAPKM | |
| SCHEMBL9321303 | 0.71 | PTGER4 (0.59) | SLC16A3PLA2G2APLA2G1BALDH1A1GAA | |
| SCHEMBL3064842 | 0.71 | PDE5A (0.76) | PDE5APLA2G2APLA2G10MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1586572-A1 | Fused pyrazolyls as anti-cancer drugs | Yung Shin Pharm. Ind. Co. Ltd. (TW) | 2005-10-19 | — | — | EP | disclosed |