SCHEMBL6356690

SCHEMBL6356690

COC(=O)N(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C1CC(C(C)C)N(C(=O)OCCO)c2ccc(C(F)(F)F)cc21

nearest known ligand 0.68

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CETP P11597 20/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6356688 1.00 CETP (0.68) CETP
SCHEMBL6275080 0.94 CETP (0.70) CETP
SCHEMBL6275078 0.94 CETP (0.70) CETP
SCHEMBL6286729 0.94 CETP (0.68) CETP
SCHEMBL6286725 0.94 CETP (0.68) CETP
SCHEMBL6274475 0.93 CETP (0.79) CETP
SCHEMBL6274478 0.93 CETP (0.79) CETP
SCHEMBL992309 0.90 CETP (0.68) CETP
SCHEMBL6182344 0.90 CETP (0.68) CETP
SCHEMBL6355057 0.89 CETP (0.65) CETP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6906082-B2 4-carboxyamino-2-substituted-1,2,3,4-tetrahydroquinolines PFIZER INC. (US) 2005-06-14 US disclosed
US-6586448-B1 Cholesteryl ester transfer protein inhibitors used as antilipemic agents for prophylaxis of cardiovascular disorders PFIZER INC. 2003-07-01 US disclosed
US-6197786-B1 ANTICHOLESTEROL AGENTS PFIZER INC 2001-03-06 US disclosed