Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.37 |
| ▸ | CASP1 | P29466 | 5/20 | 0.37 |
| ▸ | CASP7 | P55210 | 5/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.34 |
| ▸ | BAD | Q92934 | 2/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | POLR1A | O95602 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL632020 | 0.92 | CNR2 (0.39) | KDM4ECASP1CASP7HSD17B10MAPT | |
| SCHEMBL21798701 | 0.87 | POLR1A (0.41) | KDM4ECASP1CASP7HSD17B10MAPT | |
| SCHEMBL634900 | 0.85 | KDM4E (0.45) | KDM4ECASP1CASP7HSD17B10MAPT | |
| SCHEMBL634012 | 0.85 | KDM4E (0.40) | KDM4ECASP1CASP7HSD17B10MAPT | |
| SCHEMBL635320 | 0.83 | KMT2A (0.44) | KDM4ECASP1CASP7HSD17B10MAPT | |
| SCHEMBL635605 | 0.82 | TNF (0.52) | — | |
| SCHEMBL634104 | 0.80 | POLR1A (0.50) | KDM4EHSD17B10HTTALDH1A1POLR1A | |
| SCHEMBL30122318 | 0.79 | KDM4E (0.41) | KDM4ECASP1CASP7HSD17B10MAPT | |
| SCHEMBL634087 | 0.79 | KDM4E (0.41) | KDM4ECASP1CASP7HSD17B10MAPT | |
| SCHEMBL635404 | 0.79 | PTGDR2 (0.39) | KDM4ECASP1CASP7HSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1507778-B1 | ANTI-TUMOUR POLYCYCLIC CARBOXAMIDES | UNIV TROBE (AU) | 2012-02-22 | — | — | EP | disclosed |