Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.57 |
| ▸ | PPARA | Q07869 | 3/20 | 0.57 |
| ▸ | PPARD | Q03181 | 1/20 | 0.54 |
| ▸ | SOAT1 | P35610 | 3/20 | 0.51 |
| ▸ | SOAT2 | O75908 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6359084 | 0.93 | PPARG (0.59) | PPARGPPARAPPARDSOAT1SOAT2 | |
| SCHEMBL6746445 | 0.93 | PPARG (0.63) | PPARGPPARAPPARDSOAT1SOAT2 | |
| SCHEMBL6747533 | 0.85 | PPARG (0.66) | PPARGPPARAPPARDSOAT1SOAT2 | |
| SCHEMBL6358517 | 0.85 | PPARG (0.45) | PPARGPPARAPPARD | |
| SCHEMBL6744712 | 0.83 | PPARG (0.60) | PPARGPPARAPPARDSOAT1SOAT2 | |
| SCHEMBL6357812 | 0.83 | PPARG (0.43) | PPARGPPARAPPARD | |
| SCHEMBL6746999 | 0.81 | SOAT1 (0.50) | PPARGPPARAPPARDSOAT1 | |
| SCHEMBL6750140 | 0.80 | PPARG (0.62) | PPARGPPARAPPARDSOAT1SOAT2 | |
| SCHEMBL6848368 | 0.80 | PPARG (0.58) | PPARGPPARAPPARDSOAT1SOAT2 | |
| SCHEMBL5418787 | 0.80 | PPARG (0.64) | PPARGPPARAPPARDSOAT1SOAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050075377-A1 | PPAR compounds | PFIZER INC | 2005-04-07 | — | — | US | claimed |
| US-20050075377-A1 | PPAR compounds | PFIZER INC | 2005-04-07 | — | — | US | disclosed |
| EP-1372632-A1 | PROLIFERATIVE ACTIVATOR RECEPTOR (PPAR) COMPOUNDS | Pfizer Products Inc. (US) | 2004-01-02 | — | — | EP | disclosed |
| US-20020169192-A1 | PPAR compounds | HAYWARD CHERYL M (US) | 2002-11-14 | — | — | US | disclosed |
| WO-2002064130-A1 | PROLIFERATIVE ACTIVATOR RECEPTOR (PPAR) COMPOUNDS | PFIZER PRODUCTS INC. (US) | 2002-08-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020169192-A1 | PPAR compounds | PPARA, PPARG, PPARD | PPARG 2/4885PPARA 1/4885PPARD 3/4885 |
| US-20050075377-A1 | PPAR compounds | PPARA, PPARG, PPARD | PPARG 2/4885PPARA 1/4885PPARD 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.