SCHEMBL6357933

SCHEMBL6357933

c1ccc(-c2cnc3c(ccc4cccnc43)c2)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.60
CCR1 P32246 4/20 0.59
CCR8 P51685 4/20 0.59
CCR5 P51681 2/20 0.59
GMNN O75496 1/20 0.57
LMNA P02545 1/20 0.57
TP53 P04637 1/20 0.57
HSP90AA1 P07900 1/20 0.57
MMP2 P08253 1/20 0.57
CYP3A4 P08684 1/20 0.57
CYP2D6 P10635 1/20 0.57
MAPT P10636 1/20 0.57
MMP9 P14780 1/20 0.57
ALOX15 P16050 1/20 0.57
TSHR P16473 1/20 0.57
NFKB1 P19838 1/20 0.57
MMP8 P22894 1/20 0.57
THPO P40225 1/20 0.57
MTOR P42345 1/20 0.57
HTT P42858 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17125609 0.93 CCR1 (0.62) KDM4ECCR1CCR8CCR5GMNN
SCHEMBL18806859 0.93 CCR1 (0.62) KDM4ECCR1CCR8CCR5GMNN
SCHEMBL11910132 0.93 CCR1 (0.62) KDM4ECCR1CCR8CCR5GMNN
SCHEMBL23954363 0.93 CCR1 (0.67) KDM4ECCR1CCR8CCR5GMNN
SCHEMBL20726706 0.92 KDM4E (0.53) KDM4ECCR1CCR8CCR5GMNN
SCHEMBL20726702 0.92 KDM4E (0.53) KDM4ECCR1CCR8CCR5GMNN
SCHEMBL23434687 0.92 KDM4E (0.53) KDM4ECCR1CCR8CCR5GMNN
SCHEMBL23607307 0.92 KDM4E (0.53) KDM4ECCR1CCR8CCR5GMNN
SCHEMBL21841067 0.89 TOP1 (0.50) KDM4ECCR1CCR8CCR5GMNN
SCHEMBL18695350 0.89 KDM4E (0.50) KDM4ECCR1CCR8CCR5GMNN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4234539-A1 ORGANIC MATERIAL FOR AN ELECTRONIC OPTOELECTRONIC DEVICE AND ELECTRONIC DEVICE COMPRISING THE ORGANIC MATERIAL Novaled GmbH (DE) 2023-08-30 EP disclosed
EP-3524593-B1 ORGANIC MATERIAL FOR AN ELECTRONIC OPTOELECTRONIC DEVICE AND ELECTRONIC DEVICE COMPRISING THE ORGANIC MATERIAL NOVALED GMBH (DE) 2023-04-12 EP disclosed
US-20210036230-A1 Organic Material for an Electronic Optoelectronic Device and Electronic Device Comprising the Organic Material NOVALED GMBH (DE) 2021-02-04 US disclosed
EP-3533788-A1 ORGANIC MATERIAL FOR AN ELECTRONIC OPTOELECTRONIC DEVICE AND ELECTRONIC DEVICE COMPRISING THE ORGANIC MATERIAL Novaled GmbH (DE) 2019-09-04 EP disclosed
EP-3524593-A1 ORGANIC MATERIAL FOR AN ELECTRONIC OPTOELECTRONIC DEVICE AND ELECTRONIC DEVICE COMPRISING THE ORGANIC MATERIAL Novaled GmbH (DE) 2019-08-14 EP disclosed
US-9252378-B2 Organic light-emitting component OSRAM OLED GMBH (DE) 2016-02-02 US disclosed
US-20150076451-A1 ORGANIC LIGHT-EMITTING COMPONENT DOLYA HOLDCO 5 LIMITED (IE) 2015-03-19 US disclosed
CN-103262286-A Radiation-emitting organic electronic device and method for the production thereof OSRAM OPTO SEMICONDUCTORS GMBH 2013-08-21 CN disclosed
US-6929873-B2 Electroluminescent device using metal coordination compound CANON KABUSHIKI KAISHA (JP) 2005-08-16 US disclosed
US-20040013905-A1 Electroluminescent device using metal coordination compound CANON KABUSHIKI KAISHA (JP) 2004-01-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210036230-A1 Organic Material for an Electronic Optoelectronic Device and Electronic Device Comprising the Organic Material OCIAD1, OCIAD2, OR10J3 KDM4E 2264/4885CCR1 2717/4885CCR8 2294/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.