Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 13/20 | 0.53 |
| ▸ | PPARG | P37231 | 12/20 | 0.53 |
| ▸ | PPARD | Q03181 | 2/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.42 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | MLNR | O43193 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6356366 | 0.94 | PPARA (0.55) | PPARAPPARGPPARD | |
| SCHEMBL6544584 | 0.92 | PPARA (0.54) | PPARAPPARGPPARDCNR2LTB4R | |
| SCHEMBL6545379 | 0.92 | PPARA (0.54) | PPARAPPARGPPARDCNR2LTB4R | |
| SCHEMBL6361346 | 0.92 | PPARA (0.54) | PPARAPPARGPPARDCNR2LTB4R | |
| SCHEMBL6358183 | 0.91 | PPARA (0.59) | PPARAPPARGPPARDCNR2LTB4R | |
| SCHEMBL6363619 | 0.90 | PPARA (0.53) | PPARAPPARGPPARDCNR2LTB4R | |
| SCHEMBL6360237 | 0.89 | PPARA (0.52) | PPARAPPARGPPARDCNR2LTB4R | |
| SCHEMBL6545370 | 0.89 | PPARA (0.49) | PPARAPPARGPPARDCYP2D6 | |
| SCHEMBL6359745 | 0.89 | PPARA (0.49) | PPARAPPARGPPARDCYP2D6 | |
| SCHEMBL6545385 | 0.89 | PPARA (0.49) | PPARAPPARGPPARDCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050075377-A1 | PPAR compounds | PFIZER INC | 2005-04-07 | — | — | US | disclosed |
| US-20020169192-A1 | PPAR compounds | HAYWARD CHERYL M (US) | 2002-11-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020169192-A1 | PPAR compounds | PPARA, PPARG, PPARD | PPARA 1/4885PPARG 2/4885PPARD 3/4885 |
| US-20050075377-A1 | PPAR compounds | PPARA, PPARG, PPARD | PPARA 1/4885PPARG 2/4885PPARD 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.