SCHEMBL6359660

SCHEMBL6359660

CCCCCCCCOc1cc(-n2nc3ccccc3n2)c(O)c(C(C)(C)C)c1

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.39
RAB9A P51151 2/20 0.39
NR5A1 Q13285 1/20 0.39
CNR2 P34972 3/20 0.38
KDM4E B2RXH2 1/20 0.38
CNR1 P21554 1/20 0.38
GPBAR1 Q8TDU6 2/20 0.37
TLR8 Q9NR97 2/20 0.37
PLA2G2A P14555 1/20 0.36
LMNA P02545 1/20 0.36
TSHR P16473 1/20 0.36
F2R P25116 1/20 0.36
POLB P06746 1/20 0.36
PDK2 Q15119 1/20 0.35
LTA4H P09960 1/20 0.35
PTPN11 Q06124 1/20 0.35
CYSLTR2 Q9NS75 1/20 0.35
CYSLTR1 Q9Y271 1/20 0.35
IDH1 O75874 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11441445 1.00 NPC1 (0.39) NPC1RAB9ANR5A1CNR2KDM4E
SCHEMBL10879715 1.00 NPC1 (0.39) NPC1RAB9ANR5A1CNR2KDM4E
SCHEMBL21586965 0.88 NPC1 (0.40) NPC1RAB9AKDM4ELMNATSHR
SCHEMBL11136454 0.87 NPC1 (0.41) NPC1RAB9AKDM4ELMNAF2R
SCHEMBL8360557 0.87 KDM4E (0.47) NPC1RAB9AKDM4ELMNATSHR
SCHEMBL8227290 0.85 NR5A1 (0.38) NPC1RAB9ANR5A1CNR2CNR1
SCHEMBL31026341 0.84 TSHR (0.37) KDM4ETLR8PLA2G2ATSHR
SCHEMBL28348260 0.84 ESR1 (0.42) NPC1RAB9A
SCHEMBL30313741 0.84 ESR1 (0.42) NPC1RAB9A
SCHEMBL21586951 0.84 PDE2A (0.35) NPC1RAB9ACNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115803380-A Use of hydroxycinnamic acid salts for stabilizing organic materials, stabilized organic materials, method for stabilizing organic materials, specific stabilizers and stabilizer compositions 弗劳恩霍夫应用研究促进协会 2023-03-14 CN disclosed
US-20050130840-A1 INFORMATION RECORDING-DISPLAYING CARD, IMAGE PROCESSING METHOD USING SAME, AND IMAGE PROCESSOR MITSUBISHI PLASTICS, INC. (JP) 2005-06-16 US disclosed