Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 20/20 | 0.70 |
| ▸ | CCR7 | P32248 | 3/20 | 0.70 |
| ▸ | CX3CR1 | P49238 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6352231 | 1.00 | CXCR2 (0.70) | CXCR2CCR7CX3CR1 | |
| SCHEMBL6353547 | 0.94 | CXCR2 (0.63) | CXCR2CCR7CX3CR1 | |
| SCHEMBL6360635 | 0.89 | CXCR2 (0.75) | CXCR2CCR7 | |
| SCHEMBL3853081 | 0.85 | CXCR2 (0.81) | CXCR2CCR7CX3CR1 | |
| SCHEMBL3853077 | 0.85 | CXCR2 (0.81) | CXCR2CCR7CX3CR1 | |
| SCHEMBL3856676 | 0.85 | CXCR2 (0.81) | CXCR2CCR7CX3CR1 | |
| SCHEMBL5998455 | 0.83 | CXCR2 (0.80) | CXCR2CCR7CX3CR1 | |
| SCHEMBL5492987 | 0.83 | CXCR2 (0.80) | CXCR2CCR7CX3CR1 | |
| SCHEMBL6351841 | 0.82 | CXCR2 (0.67) | CXCR2CCR7CX3CR1 | |
| SCHEMBL6360524 | 0.81 | CXCR2 (0.64) | CXCR2CCR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6958344-B2 | Pyrimidine compounds and their use as modulators of chemokine receptor activity | ASTRAZENECA AB (SE) | 2005-10-25 | — | — | US | claimed |