Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16110808 | 0.84 | — | — | |
| SCHEMBL6364988 | 0.77 | XIAP (0.33) | XIAPBIRC2 | |
| Hydrochloric Acid SCHEMBL7424704 | 0.76 | XIAP (0.33) | XIAPBIRC2 | |
| Hydrochloric Acid SCHEMBL6305086 | 0.76 | XIAP (0.33) | XIAPBIRC2 | |
| SCHEMBL7427846 | 0.73 | PIK3CD (0.33) | XIAPBIRC2 | |
| Hydrochloric Acid SCHEMBL7429831 | 0.73 | PIK3CD (0.33) | XIAPBIRC2 | |
| Hydrochloric Acid SCHEMBL6309974 | 0.73 | PIK3CD (0.33) | XIAPBIRC2 | |
| SCHEMBL7425403 | 0.64 | XIAP (0.33) | XIAP | |
| SCHEMBL8330682 | 0.55 | TAAR1 (0.37) | XIAPBIRC2 | |
| SCHEMBL19548792 | 0.52 | EPHX2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050261495-A1 | Lactam Compound | AUDIA JAMES E | 2005-11-24 | — | — | US | disclosed |
| US-20040248878-A1 | Lactam compound | KOENIG THOMAS MITCHELL (US) | 2004-12-09 | — | — | US | disclosed |
| US-20040077627-A1 | Lactam compound | KOENIG THOMAS MITCHELL (US) | 2004-04-22 | — | — | US | disclosed |
| EP-1353910-A2 | LACTAM COMPOUND | ELI LILLY AND COMPANY (US) | 2003-10-22 | — | — | EP | disclosed |
| EP-1345955-A2 | LACTAM DIPEPTIDE AND ITS USE IN INHIBITING BETA-AMYLOID PEPTIDE RELEASE | ELI LILLY AND COMPANY (US) | 2003-09-24 | — | — | EP | disclosed |
| EP-1341531-A2 | LACTAM COMPOUND TO INHIBIT BETA-AMYLOID PEPTIDE RELEASE OR SYNTHESIS | ELI LILLY AND COMPANY (US) | 2003-09-10 | — | — | EP | disclosed |
| WO-2002047671-A2 | LACTAM COMPOUND TO INHIBIT BETA-AMYLOID PEPTIDE RELEASE OR SYNTHESIS | ELI LILLY AND COMPANY (US) | 2002-06-20 | — | — | WO | disclosed |
| WO-2002040508-A2 | LACTAM DIPEPTIDE AND ITS USE IN INHIBITING BETA-AMYLOID PEPTIDE RELEASE | ELI LILLY AND COMPANY (US) | 2002-05-23 | — | — | WO | disclosed |
| WO-2002040451-A2 | LACTAM COMPOUND | ELI LILLY AND COMPANY (US) | 2002-05-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040077627-A1 | Lactam compound | AAAS, BCHE, CHLSN | XIAP 3945/4885BIRC2 725/4885 |
| US-20050261495-A1 | Lactam Compound | AAAS, MASTL, APH1B | XIAP 2241/4885BIRC2 783/4885 |
| US-20040248878-A1 | Lactam compound | AAAS, CHLSN, APH1B | XIAP 2131/4885BIRC2 607/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.