Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 13/20 | 0.58 |
| ▸ | PPARG | P37231 | 11/20 | 0.58 |
| ▸ | PPARD | Q03181 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | CETP | P11597 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6359007 | 0.89 | PPARA (0.61) | PPARAPPARGPPARDCNR1CNR2 | |
| SCHEMBL6358524 | 0.86 | PPARA (0.57) | PPARAPPARGPPARD | |
| SCHEMBL6364127 | 0.86 | PPARA (0.58) | PPARAPPARGPPARD | |
| SCHEMBL6363531 | 0.86 | PPARA (0.61) | PPARAPPARGPPARD | |
| SCHEMBL6361165 | 0.86 | PPARA (0.61) | PPARAPPARGPPARD | |
| SCHEMBL6361171 | 0.86 | PPARA (0.61) | PPARAPPARGPPARD | |
| SCHEMBL6363401 | 0.86 | PPARA (0.58) | PPARAPPARGPPARD | |
| SCHEMBL6364111 | 0.85 | PPARA (0.60) | PPARAPPARGPPARDCNR1CNR2 | |
| SCHEMBL6357785 | 0.85 | PPARA (0.60) | PPARAPPARGPPARDCNR1CNR2 | |
| SCHEMBL6357788 | 0.85 | PPARA (0.57) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050075377-A1 | PPAR compounds | PFIZER INC | 2005-04-07 | — | — | US | disclosed |
| US-20020169192-A1 | PPAR compounds | HAYWARD CHERYL M (US) | 2002-11-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020169192-A1 | PPAR compounds | PPARA, PPARG, PPARD | PPARA 1/4885PPARG 2/4885PPARD 3/4885 |
| US-20050075377-A1 | PPAR compounds | PPARA, PPARG, PPARD | PPARA 1/4885PPARG 2/4885PPARD 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.