Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT1 | P26358 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | PTPRC | P08575 | 4/20 | 0.38 |
| ▸ | S100A4 | P26447 | 4/20 | 0.38 |
| ▸ | BCHE | P06276 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | CES1 | P23141 | 2/20 | 0.38 |
| ▸ | HNF4A | P41235 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29596172 | 0.74 | DNMT1 (0.46) | DNMT1ALDH1A1TSHRCYP3A4PTPRC | |
| SCHEMBL11762732 | 0.74 | NSD2 (0.47) | DNMT1ALDH1A1TSHRHPRT1CYP3A4 | |
| SCHEMBL29708071 | 0.73 | DNMT1 (0.49) | DNMT1ALDH1A1TSHRHPRT1CES1 | |
| SCHEMBL28755138 | 0.73 | DNMT1 (0.49) | DNMT1ALDH1A1TSHRHPRT1CES1 | |
| SCHEMBL8650629 | 0.73 | DNMT1 (0.49) | DNMT1ALDH1A1TSHRHPRT1S100A4 | |
| SCHEMBL10959580 | 0.73 | DNMT1 (0.49) | DNMT1ALDH1A1TSHRHPRT1PTPRC | |
| SCHEMBL8210093 | 0.73 | DNMT1 (0.49) | DNMT1ALDH1A1TSHRCYP3A4CES1 | |
| SCHEMBL11790344 | 0.73 | DNMT1 (0.49) | DNMT1ALDH1A1TSHRHPRT1CYP3A4 | |
| SCHEMBL6412225 | 0.73 | CDC25B (0.46) | ALDH1A1TSHRCYP3A4PTPRCS100A4 | |
| SCHEMBL4910366 | 0.72 | PTPRC (0.41) | ALDH1A1TSHRHPRT1CYP3A4PTPRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6846956-B2 | Triarylmethane dyes | BASF AKTIENGESELLSCHAFT (DE) | 2005-01-25 | — | — | US | disclosed |
| US-20030181740-A1 | Triarylmethane dyes | BASF AKTIENGESELLSCHAFT (DE) | 2003-09-25 | — | — | US | disclosed |