Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 16/20 | 1.00 |
| ▸ | HTR2A | P28223 | 13/20 | 1.00 |
| ▸ | HTR2B | P41595 | 7/20 | 1.00 |
| ▸ | HTR1A | P08908 | 2/20 | 0.66 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.66 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.66 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.66 |
| ▸ | HTR1D | P28221 | 1/20 | 0.66 |
| ▸ | HTR7 | P34969 | 1/20 | 0.66 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.66 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31079387 | 1.00 | HTR2C (1.00) | HTR2CHTR2AHTR2BHTR1AADRA2A | |
| SCHEMBL17504260 | 0.83 | HTR2C (0.71) | HTR2CHTR2AHTR2BHTR1AADRA2A | |
| SCHEMBL31079572 | 0.83 | HTR2C (0.71) | HTR2CHTR2AHTR2BHTR1AADRA2A | |
| SCHEMBL17504261 | 0.83 | HTR2C (0.71) | HTR2CHTR2AHTR2BHTR1AADRA2A | |
| SCHEMBL16122771 | 0.83 | HTR2C (0.71) | HTR2CHTR2AHTR2BHTR1AADRA2A | |
| SCHEMBL7771762 | 0.82 | HTR2C (0.70) | HTR2CHTR2AHTR2BHTR1AADRA2A | |
| SCHEMBL7767788 | 0.82 | HTR2C (0.70) | HTR2CHTR2AHTR2BHTR1AADRA2A | |
| SCHEMBL6365952 | 0.82 | HTR2C (0.70) | HTR2CHTR2AHTR2BHTR1AADRA2A | |
| SCHEMBL6361471 | 0.81 | HTR2C (0.68) | HTR2CHTR2AHTR2BHTR1AADRA2A | |
| SCHEMBL10252671 | 0.81 | HTR2A (0.71) | HTR2CHTR2AHTR2BHTR1AADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6956036-B1 | 6-hydroxy-indazole derivatives for treating glaucoma | ALCON, INC. (CH) | 2005-10-18 | — | — | US | disclosed |