SCHEMBL6365331

SCHEMBL6365331

CN1C(=O)N(c2ccccc2)Cc2ccccc21

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 4/20 0.50
RAB9A P51151 4/20 0.50
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
SMN1; SMN2 Q16637 3/20 0.42
HPGD P15428 2/20 0.42
LMNA P02545 2/20 0.42
CTSG P08311 5/20 0.41
CMA1 P23946 4/20 0.41
PKM P14618 2/20 0.41
SIGMAR1 Q99720 1/20 0.40
SLC6A2 P23975 1/20 0.39
SLC6A4 P31645 1/20 0.39
MAPT P10636 2/20 0.39
KDM4E B2RXH2 1/20 0.39
GAA P10253 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
FGFR4 P22455 1/20 0.38
USP2 O75604 1/20 0.38
ALDH1A1 P00352 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6365050 0.81 HPGD (0.56) NPC1RAB9AMEN1KMT2ASMN1; SMN2
SCHEMBL2536250 0.80 NPC1 (0.54) NPC1RAB9AMEN1KMT2ASMN1; SMN2
SCHEMBL3525035 0.78 BRD4 (0.47) MEN1KMT2ASMN1; SMN2HPGDSLC6A2
SCHEMBL11430704 0.77 NPC1 (0.53) NPC1RAB9AMEN1KMT2ASMN1; SMN2
SCHEMBL29929526 0.76 NPC1 (0.39) NPC1RAB9AMEN1KMT2ASMN1; SMN2
SCHEMBL11604304 0.75 NPC1 (0.48) NPC1RAB9AMEN1KMT2ACTSG
SCHEMBL6362130 0.75 NPC1 (0.48) NPC1RAB9AMEN1KMT2ACTSG
SCHEMBL5160711 0.74 MEN1 (0.50) RAB9AMEN1KMT2AHPGDLMNA
SCHEMBL6362104 0.72 HPGD (0.54) NPC1RAB9AMEN1KMT2AHPGD
SCHEMBL11604958 0.72 NPC1 (0.46) NPC1RAB9AMEN1KMT2ACTSG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1317013-B1 NON-AQUEOUS ELECTROLYTE AND SECONDARY CELL USING THE SAME MITSUBISHI CHEM CORP (JP) 2017-03-15 EP disclosed
US-6942948-B2 Nonaqueous electrolyte solution and secondary battery employing the same MITSUBISHI CHEMICAL CORPORATION (JP) 2005-09-13 US disclosed
US-20030165733-A1 Nonaqueous electrolyte solution and secondary battery employing the same MITSUBISHI CHEMICAL CORPORATION (JP) 2003-09-04 US disclosed
EP-1317013-A1 NON-AQUEOUS ELECTROLYTE AND SECONDARY CELL USING THE SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2003-06-04 EP disclosed