⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL9739864 | 0.94 | — | — | |
| Trichloroethanol SCHEMBL134202 | 0.75 | — | — | |
| SCHEMBL1086416 | 0.75 | — | — | |
| SCHEMBL5705554 | 0.72 | — | — | |
| SCHEMBL23396 | 0.72 | — | — | |
| SCHEMBL11383939 | 0.71 | TDP1 (0.31) | — | |
| SCHEMBL1964087 | 0.71 | — | — | |
| SCHEMBL186198 | 0.67 | — | — | |
| SCHEMBL1748127 | 0.67 | — | — | |
| SCHEMBL10945109 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117551086-A | Diterpene lactone derivative and preparation method thereof | 南通大学 | 2024-02-13 | — | — | CN | claimed |
| US-5527920-A | Economical manufacturing process for 1,2,3-triazoles | SYNPHAR LABORATORIES, INC. (CA) | 1996-06-18 | — | — | US | claimed |
| US-12153055-B2 | Methods of detecting and treating airway inflammatory diseases | NATIONAL JEWISH HEALTH (US) | 2024-11-26 | — | — | US | disclosed |
| CN-117551086-A | Diterpene lactone derivative and preparation method thereof | 南通大学 | 2024-02-13 | — | — | CN | disclosed |
| CN-117547527-A | Application of diterpene lactone derivative in preparation of anti-inflammatory drugs | 南通大学 | 2024-02-13 | — | — | CN | disclosed |
| CN-117547527-A | Application of diterpene lactone derivative in preparation of anti-inflammatory drugs | 南通大学 | 2024-02-13 | — | — | CN | disclosed |
| CN-117551086-A | Diterpene lactone derivative and preparation method thereof | 南通大学 | 2024-02-13 | — | — | CN | disclosed |
| US-20210333289-A1 | METHODS OF DETECTING AND TREATING AIRWAY INFLAMMATORY DISEASES | NATIONAL JEWISH HEALTH | 2021-10-28 | — | — | US | disclosed |
| EP-2905349-B1 | Ag ball, solder joint, formed solder, solder paste and silver paste | SENJU METAL INDUSTRY CO (JP) | 2017-05-17 | — | — | EP | disclosed |
| US-9266196-B2 | Ag ball, ag core ball, flux-coated ag ball, flux-coated ag core ball, solder joint, formed solder, solder paste and ag paste | SENJU METAL INDUSTRY CO., LTD. (JP) | 2016-02-23 | — | — | US | disclosed |
| EP-2905349-A2 | Ag ball, Ag core ball, flux-coated Ag ball, flux-coated Ag core ball, solder joint, formed solder, solder paste and Ag paste | SENJU METAL INDUSTRY CO., LTD. (JP) | 2015-08-12 | — | — | EP | disclosed |
| WO-2001083480-A2 | DIHYDROPYRIDINE COMPOUNDS AND METHODS OF USE | ABBOTT LABORATORIES (US) | 2001-11-08 | — | — | WO | disclosed |
| EP-1131322-A2 | DIHYDROPYRIDINE COMPOUNDS AND METHODS OF USE | ABBOTT LABORATORIES (US) | 2001-09-12 | — | — | EP | disclosed |
| WO-2000024741-A2 | DIHYDROPYRIDINE COMPOUNDS AND THEIR USE AS POTASSIUM CHANNEL OPENERS | ABBOTT LABORATORIES (US) | 2000-05-04 | — | — | WO | disclosed |
| US-5864043-A | CARDIOVASCULAR DISORDERS AND ANGIOTENSIN ANTAGONIST | KARL THOMAE GMBH (DE) | 1999-01-26 | — | — | US | disclosed |
| US-5631264-A | NEUROLOGICAL DISORDERS | SANOFI WINTHROP, INC. (US) | 1997-05-20 | — | — | US | disclosed |
| US-5554620-A | Substituted 6,11-ethano-6,11-dihydrobenzo[b] quinolizinium salts and compositions and methods of use thereof | STERLING WINTHROP INC. (US) | 1996-09-10 | — | — | US | disclosed |
| US-5541229-A | ANGIOITENSIN II ANTAGONIST AS HYPOTENSIVE AGENTS, ANTIISCHEMIC AGENTS AND CARDIOVASCULAR DISORDERS | DR. KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| US-5527920-A | Economical manufacturing process for 1,2,3-triazoles | SYNPHAR LABORATORIES, INC. (CA) | 1996-06-18 | — | — | US | disclosed |
| EP-0656359-A1 | Substituted 6,11-ethano-6,11-dihydrobenzo[b]quinolizinium salts and compositionsand methods of use thereof | STERLING WINTHROP INC. (US) | 1995-06-07 | — | — | EP | disclosed |