Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.39 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.35 |
| ▸ | TERT | O14746 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CD44 | P16070 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31387618 | 0.83 | CYP3A4 (0.63) | CYP3A4TSHRMAPK1BCHECES1 | |
| SCHEMBL29690253 | 0.83 | CYP3A4 (0.55) | CYP3A4TSHRMAPK1BCHECES1 | |
| SCHEMBL3046974 | 0.83 | CYP3A4 (0.55) | CYP3A4TSHRMAPK1BCHECES1 | |
| SCHEMBL1199708 | 0.83 | CYP3A4 (0.63) | CYP3A4TSHRMAPK1BCHECES1 | |
| SCHEMBL9068413 | 0.81 | CYP3A4 (0.46) | CYP3A4TSHRMAPK1BCHECES1 | |
| SCHEMBL10620546 | 0.79 | CYP3A4 (0.43) | CYP3A4TSHRMAPK1BCHECES1 | |
| SCHEMBL272760 | 0.78 | CYP3A4 (0.63) | CYP3A4TSHRMAPK1BCHECES1 | |
| SCHEMBL19052006 | 0.77 | POLB (0.46) | CYP3A4TSHRMAPK1POLBL3MBTL1 | |
| SCHEMBL11553026 | 0.77 | CYP3A4 (0.61) | CYP3A4TSHRMAPK1ALDH1A1TDP1 | |
| SCHEMBL2321600 | 0.76 | CYP3A4 (0.52) | CYP3A4TSHRMAPK1BCHECES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050119491-A1 | 2, 7-Substituted carbazoles and oligomers, polymers and co-polymers thereof | SHEFFIELD, THE UNIVERSITY OF (GB) | 2005-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050119491-A1 | 2, 7-Substituted carbazoles and oligomers, polymers and co-polymers thereof | CBR3, OR10J3, ORC3 | CYP3A4 1219/4885TSHR 3124/4885MAPK1 3176/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.