Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | ACE | P12821 | 3/20 | 0.49 |
| ▸ | MMP8 | P22894 | 12/20 | 0.48 |
| ▸ | MMP3 | P08254 | 6/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6368990 | 0.92 | TP53 (0.61) | TP53LMNAUSP2GAASMN1; SMN2 | |
| SCHEMBL6373299 | 0.91 | TP53 (0.60) | TP53LMNAUSP2GAASMN1; SMN2 | |
| SCHEMBL6368197 | 0.91 | TP53 (0.64) | TP53LMNAUSP2GAASMN1; SMN2 | |
| SCHEMBL6368442 | 0.90 | TP53 (0.59) | TP53LMNAUSP2GAASMN1; SMN2 | |
| SCHEMBL6375292 | 0.90 | TP53 (0.59) | TP53LMNAUSP2GAASMN1; SMN2 | |
| SCHEMBL6368940 | 0.90 | TP53 (0.59) | TP53LMNAUSP2GAASMN1; SMN2 | |
| SCHEMBL6375672 | 0.89 | TP53 (0.59) | TP53LMNAUSP2GAASMN1; SMN2 | |
| SCHEMBL6368875 | 0.88 | TP53 (0.61) | TP53LMNAUSP2GAASMN1; SMN2 | |
| SCHEMBL8292153 | 0.88 | TP53 (0.61) | TP53LMNAUSP2GAASMN1; SMN2 | |
| SCHEMBL6368880 | 0.88 | TP53 (0.61) | TP53LMNAUSP2GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6903075-B1 | Heterocyclic amide compounds as cell adhesion inhibitors | MERCK & CO., INC. (US) | 2005-06-07 | — | — | US | claimed |