Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | KDM1A | O60341 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | CKS1B | P61024 | 1/20 | 0.33 |
| ▸ | SKP1 | P63208 | 1/20 | 0.33 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.33 |
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6369268 | 1.00 | MAOB (0.39) | MAOBKDM1AKMT2AL3MBTL1MAOA | |
| SCHEMBL18606894 | 0.81 | KDM1A (0.40) | MAOBKDM1AKMT2AL3MBTL1MAOA | |
| SCHEMBL6369275 | 0.81 | MAOB (0.39) | MAOBKDM1AKMT2AL3MBTL1MAOA | |
| SCHEMBL2940110 | 0.81 | BTK (0.46) | MAOBKDM1AKMT2AL3MBTL1MAOA | |
| SCHEMBL2940111 | 0.81 | BTK (0.46) | MAOBKDM1AKMT2AL3MBTL1MAOA | |
| SCHEMBL13379232 | 0.79 | KDM1A (0.43) | MAOBKDM1AKMT2AL3MBTL1MAOA | |
| SCHEMBL2939388 | 0.78 | MAOB (0.39) | MAOBKDM1AKMT2AL3MBTL1MAOA | |
| SCHEMBL12095606 | 0.78 | MAOB (0.39) | MAOBKDM1AKMT2AL3MBTL1MAOA | |
| SCHEMBL13379250 | 0.78 | MAOB (0.39) | MAOBKDM1AKMT2AL3MBTL1MAOA | |
| SCHEMBL2939389 | 0.78 | MAOB (0.39) | MAOBKDM1AKMT2AL3MBTL1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1577301-A1 | DIAMINE DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2005-09-21 | — | — | EP | disclosed |
| EP-1415992-A1 | DIAMINE DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2004-05-06 | — | — | EP | disclosed |
| EP-1405852-A1 | DIAMINE DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2004-04-07 | — | — | EP | disclosed |