Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10445256 | 0.68 | BLM (0.39) | TSHRMAPK1HSD17B10TDP1THRB | |
| SCHEMBL5239395 | 0.66 | TSHR (0.37) | TSHRMAPK1HSD17B10TDP1THRB | |
| SCHEMBL1355407 | 0.57 | TSHR (0.42) | TSHRMAPK1HSD17B10TDP1THRB | |
| SCHEMBL13140760 | 0.57 | TSHR (0.39) | TSHRMAPK1HSD17B10TDP1THRB | |
| SCHEMBL19415938 | 0.56 | TDP1 (0.41) | TSHRMAPK1HSD17B10TDP1THRB | |
| SCHEMBL7085716 | 0.55 | TSHR (0.37) | TSHRMAPK1HSD17B10TDP1THRB | |
| SCHEMBL7672763 | 0.55 | TSHR (0.37) | TSHRMAPK1HSD17B10TDP1THRB | |
| SCHEMBL7086273 | 0.55 | TSHR (0.37) | TSHRMAPK1HSD17B10TDP1THRB | |
| SCHEMBL24042831 | 0.55 | TSHR (0.40) | TSHRMAPK1HSD17B10TDP1THRB | |
| SCHEMBL13881468 | 0.55 | TDP1 (0.40) | TSHRMAPK1HSD17B10TDP1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1577301-A1 | DIAMINE DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2005-09-21 | — | — | EP | disclosed |