Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.80 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.80 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Toluene Diisocyanate SCHEMBL28237070 | 0.94 | CYP3A4 (0.71) | CYP3A4TRPA1TDP1MAPK1TSHR | |
| Toluene Diisocyanate SCHEMBL2054278 | 0.92 | CYP3A4 (0.83) | CYP3A4TRPA1TDP1MAPK1TSHR | |
| Toluene Diisocyanate SCHEMBL27995911 | 0.90 | CYP3A4 (0.86) | CYP3A4TRPA1TDP1MAPK1TSHR | |
| Toluene Diisocyanate SCHEMBL19733056 | 0.89 | CYP3A4 (1.00) | CYP3A4TRPA1TDP1MAPK1TSHR | |
| Toluene Diisocyanate SCHEMBL28174227 | 0.89 | CYP3A4 (1.00) | CYP3A4TRPA1TDP1MAPK1TSHR | |
| Toluene Diisocyanate SCHEMBL29737260 | 0.89 | CYP3A4 (1.00) | CYP3A4TRPA1TDP1MAPK1TSHR | |
| Toluene Diisocyanate SCHEMBL29350148 | 0.89 | CYP3A4 (1.00) | CYP3A4TRPA1TDP1MAPK1TSHR | |
| Toluene Diisocyanate SCHEMBL15384 | 0.89 | CYP3A4 (1.00) | CYP3A4TRPA1TDP1MAPK1TSHR | |
| Toluene Diisocyanate SCHEMBL4905176 | 0.88 | CYP3A4 (0.96) | CYP3A4TRPA1TDP1MAPK1TSHR | |
| Toluene Diisocyanate SCHEMBL6219230 | 0.88 | CYP3A4 (0.96) | CYP3A4TRPA1TDP1MAPK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11873423-B2 | Moisture curable adhesive compositions | KANEKA AMERICAS HOLDING, INC. (US) | 2024-01-16 | — | — | US | disclosed |
| WO-2023192261-A1 | MOISTURE CURABLE ADHESIVE COMPOSITIONS | KANEKA AMERICAS HOLDING, INC. (US) | 2023-10-05 | — | — | WO | disclosed |
| US-20230265285-A1 | Moisture Curable Adhesive Compositions | KANEKA AMERICAS HOLDING, INC. (US) | 2023-08-24 | — | — | US | disclosed |
| EP-4105262-A1 | CURABLE COMPOSITION AND CURED PRODUCT THEREOF | Kaneka Corporation (JP) | 2022-12-21 | — | — | EP | disclosed |
| EP-3753984-B1 | SINGLE-COMPONENT CURABLE COMPOSITION FOR WORKING JOINT | KANEKA CORP (JP) | 2022-08-24 | — | — | EP | disclosed |
| US-20220145146-A1 | Moisture Curable Adhesive Compositions | KANEKA AMERICAS HOLDING, INC. (US) | 2022-05-12 | — | — | US | disclosed |
| EP-3931237-A1 | MOISTURE CURABLE ADHESIVE COMPOSITIONS | Kaneka Americas Holding, Inc. (US) | 2022-01-05 | — | — | EP | disclosed |
| EP-3753984-A1 | SINGLE-COMPONENT CURABLE COMPOSITION FOR WORKING JOINT | Kaneka Corporation (JP) | 2020-12-23 | — | — | EP | disclosed |
| EP-2388297-B1 | CURABLE COMPOSITION AND CURED OBJECT FORMED THEREFROM | KANEKA CORP (JP) | 2020-08-19 | — | — | EP | disclosed |
| US-10640641-B2 | Curable coating compositions of silane functional polymers | KING INDUSTRIES (US) | 2020-05-05 | — | — | US | disclosed |
| US-20070208108-A1 | Single-Component Curable Composition | KANEKA CORPORATION (JP) | 2007-09-06 | — | — | US | disclosed |
| US-20070203297-A1 | Curable Composition | KANEKA CORPORATION | 2007-08-30 | — | — | US | disclosed |
| EP-1767584-A1 | PROCESS FOR PRODUCING CURABLE RESIN COMPOSITION | Kaneka Corporation (JP) | 2007-03-28 | — | — | EP | disclosed |
| EP-1754754-A1 | CURABLE COMPOSITION | Kaneka Corporation (JP) | 2007-02-21 | — | — | EP | disclosed |
| US-20060264545-A1 | Polymer having a silicon-containing group capable of cross-linking, metal carboxylate; carboxylic acid; adhesive for interior panel, exterior panel,stone tiling, finishing ceiling, assembling electric, electronic and precision instruments, a sealant; recovery ratio, durability, creep resistance, storage | KANEKA CORPORATION | 2006-11-23 | — | — | US | disclosed |
| US-20060089432-A1 | Curable composition | KANEKA CORPORATION (JP) | 2006-04-27 | — | — | US | disclosed |
| US-20050234170-A1 | Sealant having improved dynamic durability | KANEKA CORPORATION | 2005-10-20 | — | — | US | disclosed |
| EP-1586597-A1 | Sealant having improved dynamic durability | KANEKA CORPORATION (JP) | 2005-10-19 | — | — | EP | disclosed |
| US-6486289-B1 | Curable composition | KANEKA CORPORATION (JP) | 2002-11-26 | — | — | US | disclosed |
| EP-1024170-A1 | CURABLE COMPOSITION | KANEKA CORPORATION (JP) | 2000-08-02 | — | — | EP | disclosed |